Cesarean Section Surgery, Postoperative Pain
Conditions
Keywords
postoperative pain, chronic postoperative pain, cesarean section surgery, Postpartum depression
Brief summary
Persistent postoperative pain is a globally recognized issue that deserves attention. Cesarean section is one of the surgeries that may cause persistent postoperative pain. PSPP may affect communication between mother and baby, and may lead to postpartum depression, which has a negative impact on the daily activities and quality of life of mothers. It is an important clinical issue. The main purpose of this study is to (1) prospectively investigate the overall incidence and characteristics of persistent pain after cesarean section at 3, 6, and 12 months after surgery; (2) Use regression analysis and data modeling analysis to evaluate the relationship between perioperative variables and chronic pain in postpartum women undergoing cesarean section; (3) Analyze the relationship between chronic pain after cesarean section and postpartum depression in postpartum women.
Interventions
OTHERCesarean section
Observational study without intervention
Sponsors
Huazhong University of Science and Technology
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Age range from 20 to 50 years old; * ASA grades I to III; * Full term pregnancy and planned cesarean section with transverse incision in the lower segment of the uterus; * Pregnant women who are willing to participate in this study and sign informed consent forms.
Exclusion criteria
* Have a history of dementia, mental illness, or any central nervous system disorder; * Pregnant women who are addicted to alcohol and drugs; * Difficulty in follow-up or poor patient compliance; * Has taken other investigational drugs or participated in other clinical trials in the three months prior to being selected for the study; * Serious complications occur during delivery; * Unable to cooperate with the research for any reason.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of chronic pain after caesarean section | 2024-01-01-2025-01-01 | Assessment of chronic postoperative pain by Brief Pain Inventory from 0 to ten, The higher the score, the stronger the pain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Identification of high-risk factors for postoperative inadequate analgesia and PONV in obstetric patients based on machine learning methods | 2024-2026 | Postoperative pain is represented by NRS score (0-10). The higher the NRS score, the more severe the pain. A NRS score of ≥ 4 is considered insufficient postoperative analgesia. Analyzed the predictive value of 42 variables, including preoperative, intraoperative, and postoperative variables, for postoperative inadequate analgesia. |
| Adverse effects of postoperative analgesia | 2024-2026 | Incidence and the risk factors of adverse effects of postoperative analgesia, especially postoperative nausea and vomiting |
| Checklist for Chronic pain after cesarean section | 2024-2026 | Types of chronic pain after cesarean section |
Countries
China
Contacts
Primary ContactXianwei Zhang, Doctor
Outcome results
None listed