Multiple Sclerosis
Conditions
Keywords
Minnesota manual dexterity, reliability, validity, multiple sclerosis, hand function
Brief summary
Many assessment tools have been developed and used to evaluate upper extremity functions in multiple sclerosis (MS) patients. While each test has its strengths and weaknesses, the most significant limitation of these tests is that only a limited number assess both hands simultaneously. On the other hand, most daily life activities require the coordinated use of both hands. In MS patients, bilateral impairments in hand functions can also be observed. Therefore, there is a need for bilateral assessment tools. Unlike many other assessment tools, the Minnesota Manual Dexterity Test (MMDT) allows for simultaneous evaluation of both hands. In addition to manual dexterity, it also assesses hand-eye coordination and gross motor skills. The MMDT consists of five subtests: placing, turning, displacing, single-hand turning and placing, and two-hand turning and placing. The validity of the MMDT has also been examined in MS patients. Our study aims to evaluate the reliability and validity of the MMDT in MS patients. The cutoff times that best distinguish individuals with MS from healthy individuals will also be examined. The study aims to systematically and thoroughly evaluate the MMDT, establish it as a valid and reliable method for MS patients, and provide a new perspective on assessing hand functions.
Detailed description
At baseline, the MMDT, EDSS, 9-hole peg test (9-HPT), ABILHAND survey, and Jebsen-Taylor Hand Function Test (JTHFT) will be applied to the MS group. The MMDT will be repeated seven days after the first application in MS. Healthy controls are going to perform only the MMDT.
Interventions
OTHERManual Dexterity
Individuals who meet the inclusion criteria will be evaluated for manual dexterity using MMDT, 9-HPT, ABILHAND, and JTHFT.
Individuals who meet the inclusion criteria will be evaluated for manual dexterity using MMDT on a predetermined day.
OTHERdisability level
Individuals who meet the inclusion criteria will be evaluated for disability level using EDSS
Sponsors
Cumhuriyet University
Gazi University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Age at least 18 years, * Neurologist-diagnosed Multiple Sclerosis, * Expanded Disability Status Scale (EDSS) score between 0-6.5 * No MS exacerbation within the last 3 months, * Use of stable medication in the last 3 months.
Exclusion criteria
* Having any vision, hearing or perception problems that may affect the research results, * Having an orthopedic problem that may affect manual skills in the upper extremity, * Having a cardiovascular, pulmonary disorder
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Minnesota Manual Dexterity Test | baseline (on the predetermined assessment day) | The Minnesota Manual Dexterity Test (MMDT) is a performance test designed to evaluate hand functions and hand-eye coordination both unilaterally and bilaterally, higher scores mean a worse outcome. |
| Minnesota Manual Dexterity Test-second | the second assessment will be conducted after the seven days | The Minnesota Manual Dexterity Test (MMDT) is a performance test designed to evaluate hand functions and hand-eye coordination both unilaterally and bilaterally, higher scores mean a worse outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 9-Hole Peg Test | baseline (on the predetermined assessment day) | The 9-Hole Peg Test (9-HPT) evaluates hand dexterity based on performance, higher scores mean a worse outcome. |
| ABILHAND | baseline (on the predetermined assessment day) | to assess for performance of activity. score range 0-46 point, higher scores mean a better outcome. |
| The Jebsen Hand Function Test | baseline (on the predetermined assessment day) | The Jebsen Hand Function Test (JHFT) is one of the objective and standardized tests that assesses fine motor skills and functional hand use by simulating daily living activities, higher scores mean a worse outcome. |
| The Expanded Disability Status Scale | baseline (on the predetermined assessment day) | The Expanded Disability Status Scale (EDSS) is a scale used to determine the degree of disability resulting from multiple sclerosis (MS). It evaluates eight functional domains: pyramidal, cerebellar, brainstem, sensory, bowel/bladder, visual, mental, and other functions.Score range 0-10, higher scores mean a worse outcome. |
Countries
Turkey (Türkiye)
Outcome results
None listed