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Effects of Light Intensity Physical Activities on Pre-frontal Cortical Activation, Cognitive Function, Sleepiness and Back Pain

Investigating the Acute Effects of Light Intensity Physical Activities on Pre-frontal Cortical Activation, Cognitive Function, Sleepiness and Back Pain Among Physically Inactive University Students

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06703424
Enrollment
23
Registered
2024-11-25
Start date
2024-08-11
Completion date
2024-12-31
Last updated
2026-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-frontal Cortical Oxygenated and Deoxygenated Hemoglobin Levels

Keywords

light-intensity exercise, pre-frontal cortical activation, executive functioning, university students, inactive

Brief summary

The objective of this randomised controlled trial is to examine the acute effects of two novel light intensity exercise (sit-cycling and stand-twisting) on prefrontal cortical blood oxygenation, executive functioning, sleepiness and back pain among inactive university students. The main questions it aims to answer are: * What are the changes in oxygenated haemoglobin (O2Hb) and deoxygenated hemoglobin (HHb) levels in the prefrontal cortex from baseline to immediately after and 20 minutes after a 5-min bout of S-C and S-T compared to sitting for the same duration? * What are the changes in executive functioning, specifically, n-back test and Word Colour Stroop test performance from baseline to immediately after and 20 minutes after a bout of S-C and S-T compared to sitting for the same duration? * How does participants' self-rated daytime sleepiness and back pain after a bout of S-C and S-T compare to sitting for the same duration? Participants will: * Perform sit-cycling or stand-twisting for 5 mins (experimental condition) and sit for 5 mins (control condition) * Wear the functional near-infrared spectroscopy cap on their head throughout the measurements * Complete 1-back, 2-back test and Word Colour Stroop before, immediately after and 20 minutes after experimental/ control condition * Have their blood pressure, heart rate taken by a smartwatch * Complete a daytime sleepiness questionnaire and a back pain questionnaire

Interventions

OTHERSit-cycling

Sit-cycling for 5 mins

OTHERStand-twisting

Stand-twisting for 5 mins

Sponsors

Chia Yong Hwa Michael
Lead SponsorOTHER
Sendai University
CollaboratorUNKNOWN

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
SINGLE (Subject)

Intervention model description

Two-arm intervention, crossover study design

Eligibility

Sex/Gender
ALL
Age
21 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* NTU-NIE university student, between 21 and 30 years old, do not meet physical activity guidelines (150 mins of weekly MVPA)

Exclusion criteria

* taking blood-pressure lowering medication * physically active (150 mins or more of weekly MVPA) * deemed not physically fit to participate in physical activity based on responses to Get Active Questionnaire

Design outcomes

Primary

MeasureTime frameDescription
1-back test accuracy (%)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Number of correct trials (correct recall)
1-back test reaction time (ms)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Average reaction time across trials
2-back test accuracy (%)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Number of correct trials (correct recall)
2-back test reaction time (ms)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Average reaction time across trials
Colour Word Stroop test accuracy (congruent) (%)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Number of correct trials recall
Colour Word Stroop test accuracy (incongruent) (%)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Number of correct trials recall
Colour Word Stroop test reaction time (congruent) (ms)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Average reaction time across trials
Colour Word Stroop test reaction time (incongruent) (ms)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)Average reaction time across trials
pre-frontal cortical oxygenated hemoglobin levels (micrometre)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)measured by functional near infrared spectroscopy
pre-frontal cortical deoxygenated hemoglobin levels (micrometre)Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)measured by functional near infrared spectroscopy

Countries

Singapore

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 17, 2026