Intraprosthetic Thrombus, Limb Graft Occlusion
Conditions
Brief summary
Intraprosthetic thrombus (IPT) formation and its progression to limb graft occlusion (LGO) are significant complications following endovascular aneurysm repair (EVAR). Morphological metrics based on preoperative CTA have limited predictive value for these complications. This study aims to assess the potential of computational fluid dynamics (CFD) in predicting IPT formation and its progression to LGO after EVAR.
Interventions
None listed
Sponsors
Second Affiliated Hospital of Nanchang University
Xiangya Hospital of Central South University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Aged 18 and above; 2. Patients undergone endovascular aneurysm repair; 3. Signed informed consent forms, willing to receive treatments.
Exclusion criteria
1. inflammatory aortic aneurysm; 2. patients diagnosed with connective tissue diseases; 3. patients diagnosed with atrial fibrillation; 4. patients lacking post-operative CTA; 5. Patients who are participating in other clinical projects; 6. Patients are not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Degree of intraprosthetic thrombus in limb graft | From January 2014 to June 2024 | Evaluate the area of thrombus occupying the lumen using postoperative CTA |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Disease-related complications | From January 2014 to June 2024 | Disease-related complications associated with intraprosthetic thrombus or limb graft occlusion, such as thromboembolic events |
Outcome results
None listed