Apical Periodontitis
Conditions
Brief summary
To compare the diagnostic agreement of human IL-6 chairside PoCT to ELISA in apical periodontitis undergoing endodontic therapy which could be clinically helpful to monitor the healing of periapical tissues enabling the clinician to complete the endodontic procedure, leading to a better patient care. This study will be conducted at the Conservative and Endodontics Department in Polyclinic B, Faculty of Dentistry, Manipal University College Malaysia (MUCM). It involves 30 selected patients who have single rooted tooth with apical periodontitis that undergo RCT. The collection of the exudate from the canal will be on pre and post-instrumentation. The exudated will collect twice in each instrumentation for PoCT and ELISA.
Interventions
DEVICEPoint of Care Test
PoCT as a chairside test, ELISA as a gold standard
Sponsors
Melaka Manipal Medical College
Manipal University College Malaysia
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
17 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patient having single root tooth with AP that is negative to the pulp sensitivity test * Presence of periapical lesion
Exclusion criteria
* Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Detect the IL-6 in the exudate of the tooth with apical periodontitis | 1 week | Collection of exudate in Pre-instrumentation for PoCT and ELISA . After 1 week, collection of exudate in post-instrumentation for PoCT and ELISA will be done. |
Countries
Malaysia
Contacts
Primary ContactAnchu Rachel Thomas
Outcome results
None listed