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Impact of Mindful Self-Compassion Therapy on Self Harm Behaviors, Emotional Regulation and Quality of Life Among Patients With Borderline Personality Disorder

Impact of Mindful Self-Compassion Therapy on Self Harm Behaviors, Emotional Regulation and Quality of Life Among Patients With Borderline Personality Disorder: A Randomized Controlled Trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06699732
Enrollment
70
Registered
2024-11-21
Start date
2024-09-21
Completion date
2025-12-30
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline Personality Disorder (BPD), Emotional Regulation, Psychological Distress, Quality of Life (QOL), Self Harm

Brief summary

The primary purpose of the study is to investigate whether Mindful Self-Compassion (MSC) therapy can significantly reduce self-harm behaviors, improve emotional regulation, and enhance the quality of life in individuals diagnosed with Borderline Personality Disorder (BPD). The study aims to contribute to the existing literature by providing robust evidence on the efficacy of MSC therapy for BPD, which could inform clinical practices and improve treatment outcomes

Detailed description

The current quantitative study will be carried out in two phases. A cross-sectional survey will assess quality of life, emotional regulation, psychological distress, self-harm behaviors, social support, and state of mindfulness during the first phase. A randomized controlled trial (RCT) will be done during the second phase where patients with Borderline Personality Disorder who are identified with psychological distress, low level of social support, and quality of life, will be categorized into two groups i.e. waitlist control group and intervention group through the process of randomization. Then Mindful Self Compassion therapy would be applied to participants in the intervention group. The control group is the waitlist control group so initially no intervention will be given to participants in the control group but the intervention will be given to the control group participants once the study is completed. The Mindful Self Compassion therapy would be implemented on participants using individual and in-person modes. The pre-and post-assessment will be done at Times 1 and 2 within and between control and interventional groups. After doing post-assessment the difference between pre and post-assessment will be compared to explore the efficacy of Mindful Self Compassion Therapy in patients with borderline personality.

Interventions

BEHAVIORALMindful Self Compassion Therapy

Mindful Self-Compassion (MSC) therapy is an 8-week program blending mindfulness and self-compassion to improve emotional resilience and well-being. Week 1: Introduction - Learn the basics of mindfulness, self-compassion, and reframing self-critical thoughts with kindness. Week 2: Mindfulness - Practice observing thoughts and emotions without judgment to build self-awareness. Week 3: Self-Kindness - Develop skills to treat yourself with warmth and care during difficult times. Week 4: Common Humanity - Explore shared human experiences to reduce feelings of isolation. Week 5: Working with Challenges - Learn strategies to respond compassionately to emotional pain. Week 6: Growing Compassion - Deepen compassion for yourself and others through guided exercises. Week 7: Resilience Building - Strengthen coping skills and foster emotional flexibility. Week 8: Integration - Consolidate skills to maintain self-compassion in daily life.

Sponsors

Fatima Jinnah Women University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Investigator)

Masking description

Double

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 1\. First time diagnosed non-hospitalized patients of Borderline Personality Disorder. 2\. Patients of Borderline Personality Disorder experiencing psychological distress,low level of quality of life, social support, emotional dysregulation would be included. 3\. Borderline Personality Disorder patients with age 18 years and above (both gender) from outpatient department (OPD) 4. Borderline personality patients who would be able to understand Urdu language and can give the informed consent *

Exclusion criteria

The study would have the following

Design outcomes

Primary

MeasureTime frameDescription
World Health Organization Quality of Life Scale Urdu Version3 monthsIt has 26 items and four domains: physical health (7 items), psychological health (6 items), social relationships (3 items), and environmental health (8 items); it also contains quality of life and general health items. The minimum value is 26 and the maximum value is 130. Higher scores on the scale indicate higher quality of life and low scores indicate low quality of life.

Countries

Pakistan

Contacts

PRINCIPAL_INVESTIGATORAsma Mansoor, PhD Scholar

Fatima Jinnah Women University, Rawalpindi, Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 11, 2026