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Assessing Perceptions of ML Explanations by Medical Oncologists

Survey of Medical Oncologists to Assess Trustworthiness of Various Approaches to AI Explainability for Prognostic Models

Status
Enrolling by invitation
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06699615
Enrollment
50
Registered
2024-11-21
Start date
2024-12-02
Completion date
2028-04-15
Last updated
2026-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oncology

Brief summary

The objective of this proposal is to conduct a vignette-based survey among practicing oncology clinicians who treat non-small cell lung cancer to assess the trustworthiness of explainable predictions from a neurosymbolic AI vs. State-of-the-art post-hoc explanatory algorithms, using simulated patient data.

Interventions

OTHEROnce time de-identified Qualtrics survey

Once time de-identified Qualtrics survey

Sponsors

Abramson Cancer Center at Penn Medicine
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Intervention model description

Consented participants will complete a one time de-identified Qualtrics survey.

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

"Medical oncologist" or "Hematologist/Oncologist" designation at Penn Treats lung cancer

Exclusion criteria

Non-medical oncologists No email address or physical address listed Does not treat lung cancer

Design outcomes

Primary

MeasureTime frameDescription
Determine whether neurosymbolic AI explainability methods improve the trustworthiness of explanations from a prognostic model, relative to post-hoc explainers.3 monthsOncologist will be invited to complete a vignette-based survey

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 7, 2026