Clinical Prediction Model for In-Hospital Rebleeding in Acute Non-Variceal Upper Gastrointestinal Bleeding

Construction of a Clinical Prediction Model for In-Hospital Rebleeding in Patients With Acute Non-Venous Upper Gastrointestinal Bleeding

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06697691

Enrollment

1000

Registered

2024-11-20

Start date

2024-11-22

Completion date

2024-12-31

Last updated

2024-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Non-variceal Upper Gastrointestinal Bleeding

Keywords

rebleeding, acute non-variceal upper gastrointestinal bleeding

Brief summary

ANVUGIB is a serious condition that can cause symptoms like vomiting blood or passing black stools. Although treatments have improved, about 10% to 30% of patients experience rebleeding shortly after their initial treatment, which increases the risk of death. Currently, doctors use tools like the Glasgow-Blatchford Score, Rockall Score, and AIM65 Score to predict how patients with ANVUGIB might recover. However, these tools are not very effective at identifying patients who are at risk for rebleeding. This study aims to create a new, more accurate prediction model to help doctors identify high-risk patients earlier. The investigators believe that a new predictive model, which combines patient symptoms, lab test results, and imaging findings, will improve the ability to identify patients at high risk of rebleeding compared to existing tools.The goal is to provide doctors with a more reliable tool to guide their decisions, such as when to give preventive treatments or increase monitoring. This could lead to better outcomes and reduce the risk of complications or death. This study uses patient data collected during routine care to develop and test the new model, ensuring the findings are directly applicable to real-world clinical settings.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age exceeding 18 years, * Clinical diagnosis of Acute Non-Variceal Upper Gastrointestinal Bleeding , * patients who underwent endoscopy within 24 hours of admission with confirmation of non-variceal bleeding

Exclusion criteria

* Upper Gastrointestinal Bleeding during hospitalization; * transfer from other hospitals; * variceal bleeding; * lower gastrointestinal bleeding.; * bleeding attributed to systemic diseases like disseminated intravascular coagulation (DIC) and hematological disorders; * patients with incomplete clinical data or laboratory test results; * patients who either requested early discharge or declined gastroscopy.

Design outcomes

Primary

Measure	Time frame	Description
relbeeding	up to 7 days	Rebleeding was defined as hematemesis, hematochezia, and/or melena within 7 days of the initial bleeding, accompanied by hemodynamic instability or a decrease in hemoglobin of at least 2 g/dl within 24 hours.

Countries

China

Contacts

Primary Contactjunwei yan

yanjunweifeng@163.com+8602782211449

Outcome results