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Ultrasound-based Artificial Intelligence for Classification of Carpal Tunnel Syndrome

Ultrasound-based Artificial Intelligence for Grading of Carpal Tunnel Syndrome, a Multicenter Study in China

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06697392
Enrollment
500
Registered
2024-11-20
Start date
2024-11-15
Completion date
2026-12-30
Last updated
2024-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence (AI), Carpal Tunnel Syndrome (CTS), Ultrasound

Keywords

carpal tunnel syndrome, ultrasound, artificial intelligence

Brief summary

Carpal tunnel syndrome (CTS) is one of the most prevalent peripheral neuropathies, impacting approximately 4% of the general population. It is typically classified into three degrees: mild, moderate, and severe. Accurate grading of carpal tunnel syndrome (CTS) is essential for determining appropriate treatment options, thereby playing a crucial role in optimizing patient outcomes. Electrophysiological testing (EST) is a key parameter for grading carpal tunnel syndrome (CTS). However, it is limited by several factors, including its invasive nature, poor reproducibility, and reduced sensitivity for detecting early-stage disease. Recently, ultrasound has gained widespread acceptance among clinicians for the assessment and grading of CTS. Nonetheless, radiologists often encounter challenges in this process due to the variability in image quality, differences in experience, and inherent subjectivity. To address these issues, artificial intelligence presents a promising solution. Therefore, this study aims to develop a deep learning model for grading CTS by leveraging multimodal imaging features, including B-mode ultrasound, superb microvascular imaging (SMI), and elastography. Additionally, the investigators intend to validate the model's effectiveness by testing it with images from various clinical centers, ensuring its generalizability across different clinical settings.

Interventions

OTHERultrasound examination

The investigators intend to perform ultrasound examinations for the participants with CTS.

Sponsors

Peking University People's Hospital
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* those who have complained about associated symptoms about CTS, including pain, numbness, and weakness of hand. * those who perform ultrasound examinations of median nerve within 1 week of the symptom. * those who have electrophysilogical test results as reference standard.

Exclusion criteria

* those who had a surgery in the affected hand. * those who had a trauma or fracture in the affected hand. * those who had rheumatoid-related conditions, autoimmune diseases, and endocrine disorders.

Design outcomes

Primary

MeasureTime frame
grading of CTSbaseline

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026