Lipedema
Conditions
Brief summary
1. Pilates Exercise: The Pilates method is a low-intensity form of movement based on body control, which works the body in a complete way, promoting physical and mental health. PET is different when compared to traditional exercises, which, in turn, tend to isolate the working muscles and have specific training approaches using repetitive motions. 2. Telerehabilitation: Telehealth is emerging as a key method for delivering essential healthcare. Primary care research suggests that telehealth is acceptable and has potential to overcome geographical barriers for individuals needing many times rehabilitation by eliminating the need for extensive and costly travel 3. Diet approach: A customized low-carbohydrate high-fat (LCHF) restricted caloric diet in women with lipedema will be used for 12 weeks. The LCHF diet may be a valuable nutritional strategy for lipedema and overweight/obese women, reducing inflammatory status with a beneficial effect on weight, glucose profile the concentration of triglycerides and HDL
Interventions
PROCEDUREPilates Exercise
1. Pilates Exercise: The Pilates method is a low-intensity form of movement based on body control, which works the body in a complete way, promoting physical and mental health. PET is different when compared to traditional exercises, which, in turn, tend to isolate the working muscles and have specific training approaches using repetitive motions. 2. Telerehabilitation: Telehealth is emerging as a key method for delivering essential healthcare. Primary care research suggests that telehealth is acceptable and has potential to overcome geographical barriers for individuals needing many times rehabilitation by eliminating the need for extensive and costly travel 3. Diet approach: A customized low-carbohydrate high-fat (LCHF) restricted caloric diet in women with lipedema will be used for 12 weeks. The LCHF diet may be a valuable nutritional strategy for lipedema and overweight/obese women, reducing inflammatory status with a beneficial effect on weight, glucose profile the concentration of
Sponsors
Cairo University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
35 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
1. Sixty female patients diagnosed with lipedema. 2. Their ages will range from 35-45 years old. 3. Patients diagnosed with lipedema ≥ 5 years. 4. Patients with grade 2 and 3 lipedema. 5. Patients with type 2 and 3 lipedema. 6. Patients with BMI ≥ 25 kg/m2 7. All patients will be clinically stable.
Exclusion criteria
Patient with any of the following will be excluded from the study: 1. Patients with lower limb edematous diseases such as lymphedema or chronic venous insufficiency. 2. Patients with history of previous liposuction. 3. Patients with asymmetrical lower limbs. 4. Patients with history of bariatric surgeries. 5. Patients on weight loss medications. 6. Patients any medical condition prohibiting exercise (cardiac pacemakers, diabetes mellitus, uncontrolled hypertension, and congestive heart failure) 7. Pregnant females. 8. Patients with BMI ≥ 40 kg/m2 (morbid obese). 9. Cancer patients (patients on chemotherapy, immunotherapy radiopathy). 10. Infectious diseases (HIV/AIDS, HCV, and Tuberculosis). 11. Chronic inflammatory autoimmune disease such as Sjogren's syndrome 12. Patients with neurological disorders: stroke and epilepsy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Six minutes walk test | 12 weeks | Procedures for the 6 minute walk test will be adopted from the American Thoracic Society (ATS) guidelines . 6 minute walk test is used to assess exercise tolerance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| World Health Organization's Quality of Life BREF questionnaire (QOL-BREF ). | 12 weeks | The World Health Organization (WHO) has defined quality of life as "an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns". Recently, many general instruments have been used to measure QOL in different groups (e.g., patients, workers, population and so on). One of these instruments is the World Health Organization Quality of Life BREF questionnaire (WHOQOL-BREF) questionnaire which captures many subjective aspects of QOL |
| Limb Circumference | 12 weeks | Limb Circumference: These measurements of definite points diameter in lower extremities using tape measurement are also used to predict progression and as follow up instrument |
| Body mass index (MBI) | 12 weeks | Body mass index (MBI) is used as an indicator for weight reduction |
Countries
Egypt
Outcome results
None listed