ICU, Nutrition, Paediatric
Conditions
Brief summary
This is a multi-centre prospective cohort study of nutrition in paediatric critical care in Australia and New Zealand. The study is planned to run in parallel with the adult ICU cohort study, NUTRIENT. Two study periods are proposed with the first in late 2024 and the second in 2026. This observational study seeks to determine the following (although not limited to) descriptive outcomes of interest: 1. Nutritional outcomes, including route of nutrition support (oral, enteral and/or parenteral), energy and protein prescription and provision, and anthropometric measures 2. Patient-centred outcomes, including duration of invasive respiratory support and hospitalisation, and mortality 3. Nutrition service delivery in the PICU and ward settings
Interventions
OTHERNo Intervention: Observational Cohort
No Intervention: Observational Cohort
Sponsors
Australian and New Zealand Intensive Care Research Centre
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
1. All patients \</=18 years of age 2. Admitted to the PICU after 00:00 on the day of the study period commencement 3. Admitted to the PICU for \>72 hours
Exclusion criteria
1. Those previously enrolled during the study period (i.e. those re-admitted to PICU) 2. Those for end of life care only 3. Those admitted for organ donation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Energy intake as proportion of estimated requirements | Up to day 28 of hospitalization | Oral, enteral and parenteral energy intake will be collected and reported as a proportion of estimated requirements; estimation of requirements will be standardised using the Schofield equation and dependent upon the reported phase of critical illness |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Route of nutrition provision | Up to day 28 of hospitalization | Data will be collected on route of nutrition provision (oral, enteral or parenteral); enteral route will be categorised according to type of enteral feeding route |
| Type of nutrition provision (type of diet or oral/enteral feed/formula) | Up to day 28 of hospitalization | Data will be collected on the type of nutrition provision, in regards to type of diet and the type of formula or feed provided orally or enterally |
| Anthropometric measures reported as z-scores | Up to day 28 of hospitalization | Weight and length/height will be collected (and head circumference for children up to 2 years gestational age); these measures will be reported according to WHO growth standard z-score (up to 2 years age) or CDC growth standard z-scores (2 years age and above) |
| Protein intake as proportion of estimated requirements | Up to day 28 of hospitalization | Oral, enteral and parenteral protein intake will be collected and reported as a proportion of estimated requirements; estimated requirements will be standardised and dependent upon reported phase of critical illness |
| Duration of invasive ventilation | Up to day 28 of hospitalization | Data will be collected on the duration of invasive ventilation |
| Duration of PICU and hospital admission | Up to day 28 of hospitalization | Duration of PICU and overall hospital admission will be collected |
| Multidisciplinary nutrition assessment and intervention | Up to day 28 of hospitalization | Data will be collected on the frequency of nutrition assessment or intervention, including which profession completed the assessment or intervention (i.e. dietetics, medical, nursing or other) |
Countries
Australia, New Zealand
Outcome results
None listed