Skip to content

Evaluation of Mineral Trioxide Aggregates and Grape Seeds Extract Effect on Pulpotomy

Evaluation of Mineral Trioxide Aggregates and Grape Seeds Extract Effectiveness in Pulpotomy of Primary Molars

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06694064
Enrollment
16
Registered
2024-11-19
Start date
2023-01-02
Completion date
2024-09-02
Last updated
2024-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries

Brief summary

Pediatric dentistry has always debated the benefits of vital pulp therapy. AIM: The current study was done to differentiate the histo-pathological findings of MTA versus grape seed extract in primary teeth undergoing pulpotomy as pulp dressing substances. Materials and Methods: According to the inclusion criteria, 16 primary teeth were selected in each group. Randomly and equally, the teeth were split into two groups: (MTA group) Group I, and (GSE group) Group II. After nine months, under a light microscope the teeth were evaluated and a clinical follow-up was conducted. Periapical radiographs were also taken at this time.

Interventions

PROCEDUREPulpotomy

Pulpotomy will be done for mta group

PROCEDUREextraction for histologic examination

after pulp therapy the teeth exrtracted for histologic examination

Sponsors

Al-Azhar University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
7 Years to 9 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy patients with carious primary molars

Exclusion criteria

* root resorption

Design outcomes

Primary

MeasureTime frameDescription
evaluate pain of the teeth6 monthsThe lack of any clinical indications of pulp degeneration, such as the history of spontaneous pain, pain on percussion, swelling, pathological mobility, or sinus tract

Secondary

MeasureTime frameDescription
absence of radiolucency6 monthsNo signs of periapical orfurcal radiolucency, widening of the periodontal ligament (PDL), or pathological root resorption (internal or external).

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026