Cardiovascular Surgery, Perioperative Neurocognitive Disorders
Conditions
Keywords
Perioperative Neurocognitive Disorders;Electroencephalography
Brief summary
To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia
Detailed description
Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA). Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with PND will be included in the analysis.
Interventions
PROCEDUREcardiovascular surgery
Heart bypass surgery; Heart valve replacement surgery
Sponsors
Beijing Chao Yang Hospital
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Written informed consent 2. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia 3. ASA grade: II-IV 4. older than 60 years 5. Able to complete cognitive function tests
Exclusion criteria
1. history of severe neurological diseases and psychiatric diseases 2. history of drug abuse 3. severe hearing or vision impairment 4. preoperative delirium 5. serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery 6. patients undergoing secondary surgery in a short period 7. participation in concurrent clinical trials
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery | 2025.08 | Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using The Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The predictive value of preoperative Electroencephalography features in patients with postoperative delirium following cardiovascular surgery | 2025.08 | Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . |
| Electroencephalography features in patients with postoperative delirium | 2025.08 | Electroencephalography was collected in delirium patients one week(7±2 days) after surgery. Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with postoperative delirium will be included in the analysis. |
Countries
China
Contacts
Primary ContactChangwei Wei, doctor
Outcome results
None listed