Cognitive Enhancement
Conditions
Keywords
Perceptual decision-making, Cognitive enhancement, Nootropics, EEG, Brain health
Brief summary
Nootropics are a group of medicinal substances purported to improve important cognitive functions such as learning, focus and memory. Many of these substances have demonstrated beneficial effects on cognitive performance and overall health. However, a thorough understanding of how these substances and their synergistic effects in the form of a supplement may benefit fundamental brain processes is currently lacking. In the current study, we will investigate the effects of a plant-based, nootropic supplement (https://uk.mindlabpro.com/) on perceptual decision-making (i.e. the ability to make rapid decisions based on sensory stimuli) in healthy adult participants.
Detailed description
Participants will perform a computerised cognitive task assessing their perceptual decision-making pre- and post- 60 days of continuous supplementation with either a plant-based nootropic supplement (Mind Lab pro) or placebo. During testing, electroencephalography (EEG) signals will be captured simultaneously.
Interventions
DIETARY_SUPPLEMENTNootropics (ginkgo biloba, nicergoline, piracetam, or others)
Commercially available product: Mind lab pro
DIETARY_SUPPLEMENTPlacebo
A cellulose commonly used as a bulking agent in supplement products
BEHAVIORALPerceptual decision-making performance
A computerised cognitive task involving rapid visual categorisation of images
DEVICEElectroencephalography
Brain signals are recorded from a 64 channel EEG system during the cognitive task
Sponsors
University of Leeds
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* Eligibility screening of participants was guided by the following inclusion criteria: (i) be between 20-59 years old, (ii) be right-handed and (iii) be able to cease taking other dietary supplements for two months.
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perceptual decision-making performance | Pre- and post- 60 days of supplementation | Choice accuracy and reaction times |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Brain network interdependencies | Pre- and post- 60 days of supplementation | Patterns extracted from brain signals using electroencephalography |
Countries
United Kingdom
Outcome results
None listed