Pain, Postoperative
Conditions
Keywords
Opioids, Pain Management,, Thoracic Paravertebral Block. VATS, Regional Anesthesia
Brief summary
This randomized controlled trial evaluated the efficacy of a thoracic paravertebral block (TPVB) in reducing opioid requirements and pain intensity in the PACU after video-assisted thoracoscopic surgery (VATS).
Detailed description
This randomized controlled trial evaluated the efficacy of a thoracic paravertebral block (TPVB) in reducing opioid requirements and pain intensity in the PACU after video-assisted thoracoscopic surgery (VATS). Adult patients scheduled for elective VATS who meet the eligibility criteria will be randomized to either Arm: Arm 1: General anesthesia with TPVB; Arm 2: General anesthesia alone (control group). Primary Outcome: to assess Opioid requirement in the PACU
Interventions
DRUG0.4 ml/kg of 0.5% bupivacaine
0.4 ml/kg of 0.5% bupivacaine injected into the thoracic paravertebral space
Sponsors
King Hussein Cancer Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Arm 1: General anesthesia with TPVB; Type: Experimental Intervention: 0.4 ml/kg of 0.5% bupivacaine injected into the thoracic paravertebral space. Arm 2: General anesthesia alone (control group). Type: No intervention (control) Intervention: No intervention
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients scheduled for elective VATS, ASA physical status II-III, BMI 19-40.
Exclusion criteria
* Patient refusal, coagulation disorders, contraindications to TPVB, chronic analgesic use, mental illness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Opioid requirement in the PACU | Opioid requirement assessed at 5 minutes, 15 minutes, 30 minutes post-PACU admission, and at PACU discharge (up to 4 hours) | Opioid requirement in the PACU, recorded as yes or no. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain intensity measured by Numeric Rating Scale -NRS | Pain intensity measured using the Numeric Rating Scale (NRS) at 5 minutes, 15 minutes, 30 minutes post-PACU admission, and at PACU discharge (up to 4 hours) | Pain intensity measured by Numeric Rating Scale- NRS at several time points, Range: 0 (no pain) to 10 (worst imaginable pain), Interpretation: Higher scores indicate worse pain intensity |
Countries
Jordan
Outcome results
None listed