Lens Diseases
Conditions
Brief summary
Accurately assessing and dealing with anterior segment changes in the eyes of patients with lens diseases can better guide the operation details during surgery and make reasonable plans for possible intraoperative and postoperative complications. Applying the intraoperative optical coherence tomography technique, this study analyzes the correlation between preoperative, intraoperative anterior segment structural changes and postoperative surgical effects in patients with lens diseases, and evaluates the clinical benefits of intraoperative optical coherence tomography technique in lens surgery. This study is intended to further improve the diagnosis and treatment quality of clinical lens diseases.
Detailed description
In the eyes of patients with lens diseases, there are often some special anterior segment changes, including ectopia lentis, abnormal lens morphology, and rupture of the lens capsule. These changes can be caused by ocular trauma, congenital anomalies, or be secondary to other ocular diseases and systemic diseases. Accurately assessing and dealing with these anterior segment changes can better guide the operation details during surgery and make reasonable plans for possible intraoperative and postoperative complications. This study is based on intraoperative optical coherence tomography technique, analyzes the correlation between preoperative, intraoperative anterior segment structural changes and postoperative surgical effects in patients with lens diseases, and evaluates the clinical benefits of intraoperative optical coherence tomography technique in lens surgery. This study is intended to further improve the diagnosis and treatment quality of clinical lens diseases.
Interventions
PROCEDURESurgery with Intraoperative Optical Coherence Tomography application
Surgery with the application of intraoperative optical coherence tomography technique. Intraoperative optical coherence tomography technique can provide intraocular images and show changes in intraocular structures, assisting in analyzing the correlation between preoperative, intraoperative anterior segment structural changes and postoperative surgical effects in patients with lens diseases.
PROCEDUREConventional surgery
Conventional lens surgery, without the application of intraoperative optical coherence tomography technique.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged over 18 years old, with lens opacity or abnormal position, and other conditions meeting the surgical indications, needing lens surgery treatment, with or without anterior segment structural changes.
Exclusion criteria
* Combined with other eye diseases that seriously affect visual prognosis, serious systemic diseases and other conventional contraindications for lens surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Successful implantation rate of intraocular lens | through study completion, an average of 1 year | Implantation rate of intraocular lens after surgery. |
| Intraocular lens position after implantation | 1day, 1 week and 1 month postoperation | The location of intraocular lens after surgery, observed through slit - lamp and anterior segment optical coherence tomography. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative corneal incision closure status | 1day, 1 week postoperation | Corneal incision closure status after surgery, observed through slit - lamp and anterior segment optical coherence tomography. |
| Visual function | 1day, 1 week, 1 month, 3month postoperation | Best corrected visual acuity (BCVA) measured using a decimal chart Best corrected visual acuity (BCVA) measured using a decimal chart |
Countries
China
Contacts
Primary ContactWen Xu, PHD
Outcome results
None listed