Age Problems, Cognitive Impairment, Dementia
Conditions
Brief summary
This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up. The research aims to identify risk factors as well as health and social outcomes that are associated with cognitive impairment in elderly populations, and independently develop AI-assisted software and applications for cognitive enhancement and physical rehabilitation training.
Detailed description
This is a community-based prospective cohort study in Hainan Province, China. Subjects are individuals aged 60 years and above who have lived in the communities for more than six months and have signed informed consent. The research have been initialed in 2023 and aims to identify the risk factors associated with cognitive impairment, to develop software for cognitive enhancement and physical rehabilitation training. The study includes three steps: first, to conduct cognitive function screening in 16 communities in four districts (Xiuying, Meilan, Longhua, and Qiongshan) of Haikou City and establish a database for the elderly in tropical regions; second, to identify risk factors associated with cognitive impairment in the elderly population; finally, to independently develop a software for cognitive function enhancement and physical rehabilitation training.
Interventions
OTHERNo Intervention: Observational Cohort
There were no interventions in our cohort. The subjects of our cohort were and will be followed up at the regular intervals.
Sponsors
The Second Affiliated Hospital of Hainan Medical University
Xuanwu Hospital, Beijing
Fudan University
Hainan Medical College
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
60 Years to 120 Years
Healthy volunteers
Yes
Inclusion criteria
* Inclusion Criteria: * Age 60 years and above * Lived in the community for more than 6 months * Signed the informed consent form *
Exclusion criteria
* Cannot complete the survey
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The prevalence and incidence of cognitive impairment base on the communities | An average of 1 to 2 years | Mild cognitive impairment was measured using a Chinese version Mini-Mental State Examination, which was collected by questionnaire. The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the cognition outcome. |
| The prevalence and incidence of dementia using a population-based survey | An average of 1 to 2 years | Dementia was determined by diagnosis of hospitalization or Clinical Dementia Rating Scale (Montreal Cognitive Assessment, MoCA). The minimum value of the MoCA is 0, and the maximum value is 30, the higher the score, the better the outcome. In addition, subtypes of dementia will be based on the specific clinical diagnosis. |
| The conversion rate of normal to cognitive impairment | An average of 1 to 2 years | Percentage of enrolled population that convert from normal to cognitive impairment |
| The conversion rate of cognitive impairment to dementia | An average of 1 to 2 years | Percentage of enrolled population that convert from cognitive impairment to dementia |
Countries
China
Contacts
Primary ContactJindong Ding Petersen, PHD.
Outcome results
None listed