Skip to content

Triple Recipient Strategy Using Split, Domino, and Auxiliary Techniques

Expanding Donor Liver Utilization: a Case Series Study of Triple Recipient Strategy Using Split, Domino, and Auxiliary Techniques.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06683820
Enrollment
3
Registered
2024-11-12
Start date
2023-04-02
Completion date
2024-04-02
Last updated
2024-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma (HCC)

Keywords

Split liver transplantation, Domino liver transplantation, Auxiliary liver transplantation, Argininemia, Cirrhosis, Hepatocellular carcinoma

Brief summary

The investigators report a case of the simultaneous use of split liver transplantation (SLT), domino liver transplantation (DLT) and auxiliary liver transplantation (ALT) to achieve one donor for three recipients.

Detailed description

The investigators report a case of the simultaneous use of split liver transplantation (SLT), domino liver transplantation (DLT) and auxiliary liver transplantation (ALT) to achieve one donor for three recipients. Three recipients had hepatitis C cirrhosis, argininemia, and hepatocellular carcinoma (HCC), respectively. The investigators performed SLT in the first two recipients (an adult and a child), with the donor liver coming from a female who died of severe head trauma. The right lobe of the child, as the domino liver graft, was transplanted to the postoperative HCC patient, whose left lateral lobe was preserved after tumor resection. All recipients were discharged from the hospital. During the 12 months of follow-up, all three recipients remained alive.

Interventions

None listed

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* liver cirrhosis * argininemia * hepatocellular carcinoma

Exclusion criteria

* Patients who do not require an allogeneic liver transplantation.

Design outcomes

Primary

MeasureTime frameDescription
Postoperative survival time2023/04-2024/04The duration of time a patient survives after undergoing a surgical procedure.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026