Myopia
Conditions
Keywords
myopia, red-light, distant-image screen
Brief summary
This study aims to assess the efficacy and safety of daily exposure to 650-nm low-level red light (RL) and distant-image therapy (DIT) for myopia treatment.
Detailed description
This was a randomized clinical trial. Children aged 8 to 10 years with a spherical equivalent error (SER) ranging from -1 to -1.5 diopters (D) were enrolled, and were randomly allocated to the following treatment group: RL, DIT, RL plus DIT, and control in a 1:1:1:1 ratio. The primary outcomes were one-year change in SER and axial length.
Interventions
DEVICEred light and distant image screen
red light plus distant image screen, children use these two devices at the same time
DEVICEred light
children use red light for 3 minutes each time, twice a day
DEVICEdistant image screen
Children in this group were asked to use this device for ≥1 hour/day
Sponsors
Beijing Tongren Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
8 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* 1\. Age between 8 and 10 years old. 2. The spherical equivalent error after pupil dilation was between -1.0 D and -1.5D. 3\. Corneal astigmatism ≤ 1.25D. 4. Interocular refraction discrepancy ≤ 1.5D. 5. Near-distance exophoria \< 10 prism diopters (△) and far-distance exophoria \< 6 prism diopters (△). 6\. Willingness to participate in the study and signed informed consent.
Exclusion criteria
* 1\. Intraocular pressure was below 10 mmHg or higher than 22 mm Hg. 2. Presence of amblyopia, or ocular pathological conditions such as retinal, lens, or corneal disorders. 3\. Children currently using atropine or orthokeratology for myopia control. 4. Patients with systemic and immune disorders such as albinism, psoriasis, nephrotic syndrome, systemic lupus erythematosus, diabetes, etc. 5\. Individuals with conditions like Tourette's syndrome or epilepsy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in axial length | one year | Axial length was measured using an optical biometer (Colombo IOL, Moptim) |
| Changes in spherical equivalent error | one year | Spherical equivalent error was calculated from the dioptric powers of the sphere and half of the cylinder.The children's pupils were dilated using tropicamide eyedrops, then SER was subsequently measured using an auto refractor (ARK-510A, Nidek Co Ltd) |
Countries
China
Outcome results
None listed