Skip to content

High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort)

High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06682507
Acronym
HOPE
Enrollment
5000
Registered
2024-11-12
Start date
1996-01-01
Completion date
2050-12-31
Last updated
2024-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lupus Nephritis (LN)

Keywords

lupus, lupus nephritis, outcomes, end stage kidney disease

Brief summary

The goal of this observational study is to learn about the long-term renal and patient's survival of lupus nephritis (LN) patients in China. The main question it aims to answer is: Does the renal and patient's survival improved in the long term period? Participants who had renal biopsy proven lupus nephritis in one hospital will be followed up.

Detailed description

Patients from 1996-2016 were retrospective enrolled and patients starting from 2017 were prespective enrolled

Interventions

OTHERNo Intervention: Observational Cohort

No Intervention: Observational Cohort

Sponsors

First Affiliated Hospital, Sun Yat-Sen University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
14 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients who had biopsy proven lupus nephritis in The First Affiliated Hospital of Sun Yat-sen University

Exclusion criteria

* less than 14 years old * refused to give written consent

Design outcomes

Primary

MeasureTime frameDescription
Rate of patients with end stage renal diseaseFrom data of enrollment until the data of first documented end stage renal disease, assessed up to 50 yearsEnd stage renal disease

Secondary

MeasureTime frameDescription
Rate of patient's mortalityFrom data of enrollment until the data of death, assessed up to 50 yearsdeath

Countries

China

Contacts

Primary ContactXi Xia, MD PHD
xiax29@mail.sysu.edu.cn+8618825134511
Backup ContactRuihan Tang, MD PHD
tangrh8@mail.sysu.edu.cn+8618998472466

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026