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Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding

Utilizing of Physiological Parameters And Derived Indices to Predict The Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06680583
Acronym
SI
Enrollment
150
Registered
2024-11-08
Start date
2024-11-01
Completion date
2027-03-11
Last updated
2026-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal Bleeding, Liver Cirrhosis

Keywords

cirrhosis, gastrointestinal bleeding, physical indicator, shock index

Brief summary

Can physiological indicators such as quick Sequential Organ Failure Assessment , Shock Index, and its derived indicators such as Modified Shock Index , Age Shock Index and Respiratory Adjusted Shock Index accurately predict the prognosis of cirrhosis patients with gastrointestinal bleeding? To explore the improvement of emergency and critical care patient management.

Detailed description

Cirrhosis is a common chronic liver disease with gastrointestinal bleeding being one of its complications. Gastrointestinal bleeding is quite common in patients with cirrhosis, but its prognosis is difficult to accurately predict. In current clinical practice, critical care physicians often use physiological indicators to assess the risk level of patients. Among them, the Shock Index and its derived indicators such as the Modified Shock Index, Age Shock Index, and Respiratory Adjusted Shock Index have been widely used in other fields, but their actual value in patients with cirrhosis complicated by gastrointestinal bleeding is not yet clear. The prognosis of cirrhosis patients with gastrointestinal bleeding affects the quality of life and survival of the patients, thus necessitating the establishment of a reliable prognostic assessment tool to assist critical care physicians in making rapid treatment decisions. The motivation of this study is to explore the application value of Shock Index-related indicators in predicting the prognosis of cirrhosis patients with gastrointestinal bleeding, in order to improve the medical efficiency for this specific group of critically ill patients.

Interventions

OTHERphysical indicators such as shock index relatives

shock index relatives indicators used in the prediction of cirrhosis with gastrointestinal bleeding

Sponsors

St. Martin De Porress Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

cirrhosis with gastrointestinal bleeding -

Exclusion criteria

no complete medical record and trauma patient \-

Design outcomes

Primary

MeasureTime frameDescription
shock index= heart rate / systolic blood pressure normal range:0.5-0.7 Modified shock index = heart rate/mean arterial pressure(MAP) age shock index = SI x age number respiratory adjusted shock index(RASI) = HR/SBP × RR/10. MAP = DP + 1/3(SP - DP)through study completion, an average of 6 monthsfind the shock index relatives indicators in the prognosis prediction of cirrhosis with gastrointestinal bleeding

Countries

Taiwan

Contacts

CONTACTChia-Hsi Chen, Physician
urologist3509@gmail.com886-5-2756000
CONTACTChung-Jing Wang, professor
medicine@stm.org.tw886-5-2756000
STUDY_DIRECTORYeong-Chin Jou Jou, professor

St. Martin De Porres Hospital Education and Research

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 18, 2026