Inflammatory Bowel Diseases
Conditions
Keywords
IBD, lipid metabolism, activity
Brief summary
This study aimed to demonstrate the characteristic lipid profile changes in patients with inflammatory bowel disease.
Detailed description
This study aimed to demonstrate the characteristic lipid profile changes in patients with inflammatory bowel disease. The investigators followed up with patients with different stages of IBD and collected plasma and lesion tissues from patients and healthy volunteers for lipid metabolism-related substances to assess the changes in lipid metabolism in patients with different stages of IBD and their impact on disease.
Interventions
None listed
Sponsors
First Affiliated Hospital of Harbin Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with inflammatory bowel disease; aged 18-80 years; all cases agreed to participate in the study. * Healthy volunteers who agreed to participate in the study.
Exclusion criteria
* Patients with severe heart disease; patients with severe kidney disease; patients with low blood pressure; patients with severe infections such as sepsis or pneumonia; patients who have used immunosuppressants such as 6-mercaptopurine, imidazole thiopurine, and cyclosporine within a short period, and women during pregnancy; patients who are post-colon resected; patients who disagreed to participate in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Differential lipid composition between disease and healthy groups | 14 weeks | Differences in lipid composition between disease and healthy groups. |
| Differences in lipid composition between active and remission disease | 14 weeks | Differences in lipid composition between active and remission disease |
Countries
China
Contacts
Primary ContactHuichao Zhang, MD
Outcome results
None listed