Periodontal Disease
Conditions
Keywords
inflamaging
Brief summary
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
Detailed description
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
Interventions
PROCEDUREconventional scaling and debridement
conventional scaling and debridement
Diode laser as adjunctive to conventional scaling and debridement
Sponsors
Rawda Saleh Saad Alashmawy
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Male or Female 2. Aged below 40 or above 60. 3. Have at least 16 natural teeth excluding wisdom. 4. Provide informed consent and willingness to cooperate with study protocol. 5. Periodontitis stage II patients (23): * CAL from 3-4 mm. * Radiographic bone loss (15% to 33%). * No tooth loss due to periodontitis. * Maximum probing depth ≤ 5 mm, mostly horizontal bone loss
Exclusion criteria
* 1- Patients with any smoking habits 2- History of antibiotics in the previous three months. 3- Pregnant or lactating female. 4- Treatment with any systemic drug. 5- History of systemic disease. 6- Patients who received periodontal treatment in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical attachment loss | Base line , follow up after 1 month , second follow up after 6 months |
| Gingival index | base line, follow up after 1 month, second follow up after 6 months |
| Toll like receptor - 4 | base line, follow up after 1 month, second follow up after 6 months |
Countries
Egypt
Outcome results
None listed