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Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review

A Systematic Review of COVID-19's Impact on Pregnancy Outcomes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06677281
Acronym
COVID-PREG
Enrollment
1
Registered
2024-11-06
Start date
2024-05-03
Completion date
2024-08-25
Last updated
2024-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19, Maternal Health, Neonatal Health, Pregnancy Outcomes

Brief summary

This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health. The review focuses on key outcomes such as preterm birth, maternal complications, and neonatal health, utilizing comprehensive literature from peer-reviewed journals. By analyzing existing studies, we aim to identify trends and gaps in research regarding COVID-19 and pregnancy. This review is intended to inform healthcare providers and pregnant individuals about potential risks and considerations during the pandemic.

Interventions

OTHERSystematic Review of COVID-19's Impact on Pregnancy Outcomes

This study is a systematic review of existing literature that examines the effects of COVID-19 on pregnancy outcomes, including maternal health, neonatal health, and obstetric complications. It synthesizes data from various studies to provide an overview of the potential risks associated with COVID-19 infection during pregnancy. This intervention does not involve any new clinical trials or direct patient interaction.

Sponsors

Zahedan University of Medical Sciences
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* Pregnant individuals diagnosed with COVID-19. * Studies reporting pregnancy outcomes related to COVID-19 published between January 2020 and the present. * Articles that include quantitative data on maternal and fetal outcomes.

Exclusion criteria

* Studies that do not report on COVID-19-related pregnancy outcomes. * Non-peer-reviewed articles or grey literature. * Research focusing on non-pregnant populations.

Design outcomes

Primary

MeasureTime frameDescription
Impact of COVID-19 on Maternal and Neonatal OutcomesThe review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.This primary outcome measure evaluates the various maternal and neonatal outcomes associated with COVID-19 infection during pregnancy. Key metrics include rates of maternal morbidity, neonatal morbidity, preterm birth, low birth weight, and any documented complications during pregnancy, labor, and delivery. The systematic review aims to synthesize data from available studies to provide a comprehensive understanding of these outcomes and their implications for clinical practice.

Secondary

MeasureTime frameDescription
Effects of COVID-19 on Pregnancy-Related ComplicationsThe review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.This secondary outcome measure assesses the frequency and types of pregnancy-related complications associated with COVID-19. This includes conditions such as gestational hypertension, gestational diabetes, placental abruption, and other adverse effects that may arise during the pregnancy period. The review aims to analyze the incidence of these complications in pregnant individuals diagnosed with COVID-19 compared to non-infected counterparts, providing insights into how the virus may impact overall pregnancy health.

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026