Advanced Periodontitis, Stage III Periodontitis, Stage IV Periodontitis
Conditions
Keywords
periodontitis, clinical attachment loss, advanced periodontitis
Brief summary
This study will be carried out to compare between the effect of 4%Tulsi gel and 1%Chlorohexidine gel as locally administered agents in the treatment of advanced periodontitis. Clinical parameters measurements, microbiological and radiographic assessment will be performed at base line, one month and 3 months after the intervention.
Interventions
DRUGTulsi gel
After scaling and root debridement, 4% of Tulsi gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
After scaling and root debridement, 1% of Chlorhexidine gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
30 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* All patients included in this study will be having advancedI Periodontitis * Aging from 30 to 50 years old * Free from any local or systemic risk factors that may affect the results of the study.
Exclusion criteria
* Long-term therapy with medications within a month prior to enrollment that could affect periodontal status or healing. * Pregnant woman and lactating mothers. * Patients with previous periodontal treatment including scaling and root planning and periodontal surgery in the last 3 and 6 months, respectively.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical parameters | 3 months after end of treatment | Improvement of the clinical attachment loss in millimeters. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Microbiological assessment | 3 months after end of treatment | Counting microbial colony of Porphyromonas gingivalis |
Countries
Egypt
Outcome results
None listed