Weaning Failure
Conditions
Keywords
Massimo
Brief summary
Weaning induced cardiac dysfunction is a common cause of weaning failure in critically ill patients. plethysmography variability index (PVI) is a non-invasive, real-time, and automated parameter for evalu¬ating fluid responsiveness. By proving the validity of (PVI) in predicting successful spontaneous breathing trial Massimo can be used an easy noninvasive method that help in deciding the right time for weaning.
Interventions
DEVICEmassimo
measure plethysmography variability index in patients on spontaneous trial planning for extubation and evaluate its sensitivity in relation to transthoracic echocardiographic velocity time integral in early detecting weaning induced pulmonary edema
Sponsors
Ain Shams University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
1. Intubation and mechanical ventilation 2. Fulfilling criteria for extubation 3. Fraction inspired oxygen less than 50%
Exclusion criteria
* a. Hemodynamic instability b. b. tracheostomy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| accuracy of change PVI in detecting volume responsiveness | 1 hour | accuracy of change PVI in detecting volume responsiveness through measuring limits of agreement , Bias and correlation between PVI and a standard method of measurement which left ventricular outflow tract velocity time integral |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sensitivity of trend of changes in hemoglobin by Massimo to detect WIPO and | 1 hour | — |
| time in minutes between rise of hemoglobin and clinical diagnosis of WIPO | 1 hour | minutes between rise of blood hemoglobin concentration measured by Massimo and clinical diagnosis of WIPO |
Countries
Egypt
Outcome results
None listed