High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome

Prediction of Acute Coronary Syndrome In-hospital Major Adverse Cardiovascular Events by High Sensitivity C- Reactive Protein to Albumin Ratio

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06673381

Enrollment

240

Registered

2024-11-04

Start date

2024-11-01

Completion date

2025-10-01

Last updated

2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Keywords

high sensitive c-reactive protein to albumin ratio

Brief summary

assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients

Detailed description

Observational study conducted at coronary care unit(CCU) in sohag university hospital It included patients with ACS diagnosed according to AHA/ACCF guidelines (according to symptoms, ECG findings and serum troponin levels), who had admitted to the CCU. Venous blood samples were instantly collected on admission to the hospital. hs-CRP , serum albumin level were measured. hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR) In-hospital MACE was regarded as the end point of our study. It was defined as acute heart failure, cardiogenic shock, reinfarction, all-cause death, serious arrhythmia and cardiac death

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients aged 18 Year or older presented by ACS not candidet for primary percutaneus coronary intervention ( PCI ) .

Exclusion criteria

* • Patients aged \< 18 years old * Patients who have eGFR \<60 ml/kg /m2 * Patients who have malignancies * Patients who have chronic heart failure (NYHA class \>II) * Pateints who have chronic liver disease * Patients who have nephrotic syndrome * Patients who have acute cerebrovascular stroke * Pregnant women * Patients who have recent infection

Design outcomes

Primary

Measure	Time frame	Description
assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in acute coronary syndrom patients	at time of admission in hospital	Venous blood samples were collected on admission to the hospital. hs-CRP , serum albumin level were measured. hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR)

Countries

Egypt

Contacts

Primary ContactAmira Elbasuony, resident

amiraelbadawy518@gmail.com01113695925

Outcome results