HIV Infection, MDR-TB
Conditions
Brief summary
This study aims to investigate the relationship between HIV infection and multi-drug resistant tuberculosis (MDR-TB) among affected individuals in Zahedan, Iran. It will involve a detailed analysis of patient demographics, clinical characteristics, and treatment outcomes to enhance understanding of this co-infection. The findings may inform better treatment strategies and healthcare policies for managing these diseases in similar populations.
Interventions
OTHERExamination of HIV Infection in Patients with Multi-Drug Resistant Tuberculosis (MDR-TB)
This meta-analysis examines the impact of HIV infection on the prevalence and outcomes of multi-drug resistant tuberculosis (MDR-TB) among affected populations. The analysis synthesizes data from multiple studies conducted across various countries, focusing on the correlation between HIV co-infection and MDR-TB rates, treatment outcomes, and demographic factors. The findings aim to enhance understanding of the complex interactions between HIV and MDR-TB, ultimately informing clinical practices and public health strategies.
Sponsors
Zahedan University of Medical Sciences
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (aged 18 years and older) diagnosed with both HIV and multi-drug-resistant tuberculosis (MDR-TB). * Studies published in peer-reviewed journals. * Studies that provide data on the co-occurrence of HIV and MDR-TB. * Participants from diverse geographical regions to enhance generalizability. * Studies with clear definitions of MDR-TB according to WHO guidelines.
Exclusion criteria
* Studies that focus solely on drug-susceptible tuberculosis without MDR-TB. * Studies involving pediatric populations (under 18 years of age). * Non-original research such as reviews, editorials, and commentaries. * Studies lacking sufficient data on the co-occurrence of HIV and MDR-TB. * Studies that do not adhere to ethical guidelines for human subjects or lack appropriate ethical approvals.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of Multi-Drug Resistant Tuberculosis (MDR-TB) in HIV-Positive Patients | Data collected over the course of the studies from 2006 to 2018. | This study aims to determine the prevalence of multi-drug resistant tuberculosis (MDR-TB) among patients co-infected with HIV. Data will be collected from various studies included in the meta-analysis, focusing on the incidence rates of MDR-TB in this population. The analysis will provide insights into the challenges faced in treating HIV-positive individuals with MDR-TB and highlight the need for targeted interventions. |
Countries
Iran
Outcome results
None listed