Anal Cancer
Conditions
Keywords
HPV prevalence, HPV genotype, Anal cancer
Brief summary
To demonstrate HPV prevalence and its genotype distributions in anal cancer in China and to describe demographic and clinical features of HPV-related anal cancer in China; To describe the epidemiological characteristics ,trends and of disease burden of anal cancer in China
Interventions
None listed
Sponsors
Fudan University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* (1) Patients diagnosed with anal cancers, (2) Patients without radiation or chemotherapy prior to specimen collection;
Exclusion criteria
* (1) Patients with HIV infection, (2) Patients with immunosuppression after solid organ transplantation, (3) Those who do not agree to specimen collection and testing, (4) For retrospective study cases, those who without specimen.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence and types of distribution of HPV | From enrollment to pre-treatment | — |
| Incidence of anal-cancers-associated complications | From enrollment to pre-treatment | with or without HPV infection by subgroups of sex, age at diagnosis, sexual orientation, and stage at diagnosis (Stage I, II, III, IV, unknown) |
| Routine laboratory testing results | From enrollment to pre-treatment | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence rates of anal cancer in China | From enrollment to pre-treatment | overall and for 5-year calendar periods 2001-2005, 2006-2010, and 2011-2015 |
| Mortality rate of anal cancer in China | From enrollment to pre-treatment | overall and for 5-year calendar periods 2001-2005, 2006-2010, and 2011-2015 |
| Annual percentage changes (APCs) and average APCs (AAPCs) | From enrollment to pre-treatment | — |
Countries
China
Contacts
CONTACTYing Zheng
Outcome results
None listed