Role of Apfel's Score in Predicting Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06669325

Enrollment

100

Registered

2024-11-01

Start date

2022-03-12

Completion date

2023-10-28

Last updated

2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

APFEL RİSK SCORE, Post Operative Nausea and Vomiting (PONV)

Brief summary

The goal of this observational study is to assess the role of Apfel's score in predicting postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis. The main questions it aims to answer are: 1. Does Apfel's score accurately predict the occurrence of PONV after laparoscopic cholecystectomy? 2. Which components of Apfel's score are most strongly associated with PONV? Participants will undergo laparoscopic cholecystectomy under general anesthesia. Researchers will calculate each participant's Apfel score preoperatively, and postoperative outcomes, such as nausea and vomiting, will be monitored for 24 to 48 hours. Researchers will compare PONV incidence among patients with varying Apfel scores to determine if higher scores correlate with a higher risk of PONV.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Patients aged 18 to 90 years. * Patient scheduled for elective laparoscopic cholecystectomy for symptomatic cholelithiasis. * Patients who provided written informed consent to participate in the study.

Exclusion criteria

* Patients receiving prophylactic antiemetic medications prior to surgery. * Patients on opioid analgesics for reasons other than the surgical procedure. * Pregnant women. * Patients whose laparoscopic cholecystectomy was converted to open cholecystectomy during the operation.

Design outcomes

Primary

Measure	Time frame	Description
Incidence of Postoperative Nausea and Vomiting (PONV)	Assessed for 24 hours post-surgery.	The number of patients who experience nausea and/or vomiting within 24 hours after laparoscopic cholecystectomy.

Secondary

Measure	Time frame	Description
Relationship Between Apfel's Score and PONV Incidence	Assessed for 24 hours post-surgery.	Evaluating the correlation between the Apfel's score (0-4) and the likelihood of PONV in patients after surgery.

Countries

Nepal

Outcome results