Antibiotic-associated Diarrhea, Diarrhea
Conditions
Keywords
antibiotic-associated diarrhea, children zinc, probiotics, zinc, probiotics
Brief summary
The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
Detailed description
The participants will be children aged 3 months to 3 years.The zinc group received oral zinc supplementation; 2.5 ml every 12 hours for children aged \<1 year and 5 ml every 12 hours for older children; the probiotics group received oral probiotics; 1 probiotic sachet; and the control group received nothing.
Interventions
DIETARY_SUPPLEMENTZinc Supplement, probiotic
received oral zinc supplementation; 2.5 ml every 12 hours for children aged \<1 year and 5 ml every 12 hours for older children; the probiotics group received oral probiotics; 1 probiotic sachet
Sponsors
Hormozgan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Intervention model description
Randomly assigned to three groups of equal size, exclusively receiving the standard antibiotic regimen or the zinc and probiotics groups
Eligibility
Sex/Gender
ALL
Age
3 Months to 3 Years
Healthy volunteers
Yes
Inclusion criteria
1. children aged 3 months to 3 years 2. prescribed antibiotics for various medical conditions
Exclusion criteria
1. Diarrhea, Dysentery 2. Underlying chronic disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of Antibiotic-Associated Diarrhea | 6 month | Passing loose, watery stools three or more times a day after taking antibiotic by questionnaire. |
Countries
Iran
Outcome results
None listed