Knee Osteoarthritis
Conditions
Keywords
Resistance Training, Knee Osteoarthritis, Pain
Brief summary
This study aim to evaluate pain after different resistance training protocols (placebo, 4 sets of 10RM, 8 sets of 10 RM and 12 sets of 10RM) in patients with severe knee osteoarthritis.
Interventions
OTHERResistance Exercise
10 Repetition Maximum (RM)
OTHERPlacebo
No exercise
Sponsors
University of Valencia
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
55 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* men and women at least 55 years old * diagnosed with severe knee OA * scheduled for unilateral Total Knee Arthroplasty (TKA) surgery
Exclusion criteria
* pain in the contralateral (non-studied) limb (maximum ≥80 of 100 mm on a visual analog scale (VAS) during daily activities) * another hip or knee joint replacement in the previous year * any medical condition in which exercise was contraindicated * participated in exercise programs (\>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study * history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of study tasks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in self-reported pain intensity | Pre-exercise (pre), immediate post exercise (post), and 10 min after exercise (post 10min) | Measure of knee pain intensity with the Visual Analogue Scale (0-100mm), with higher scores reflecting higher perceived pain intensity |
| Change in pressure pain thresholds | Pre-exercise (pre), immediate post exercise (post), and 10 min after exercise (post 10min) | Measured with a mechanical algometer (Wagner Instruments, Greenwich, CT, USA) in three sites (vastus medialis of the affected limb, vastus medialis of the unaffected limb, and distal to the non-dominant arm lateral epicondyle) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| WOMAC questionaire | pre-exercise | A self-administered questionnaire for patients with hip or knee osteoarthritis. contain 24 items grouped into three dimensions: pain (5 items), stiffness (2 items) and physical function (17 items). Higher scores on the WOMAC indicate worse pain, stiffness, and functional limitations. |
| Tampa Scale of Kinesiophobia (TSK 11) | pre-exercise | Measure fear of movement and its score ranges from 11-44 with higher scores indicate an increasing degree of kinesiophobia |
| Chronic Pain Self-Efficacy Scale | pre-exercise | Measures three domains of pain self-efficacy: pain management, physical functioning, and coping with symptoms management, physical functioning, and coping with symptomsmanagement, physical functioning, and coping with symptoms. A higher score suggests higher self-efficacy |
| Pain Catastrophizing Scale | pre-exercise | People are asked to indicate the degree to which they have certain thoughts and feelings when they are experiencing pain using the 0 (not at all) to 4 (all the time) scale. A total score is yielded (ranging from 0-52), along with three subscale scores assessing rumination, magnification and helplessness, with higher scores reflecting worse condition. |
Countries
Spain
Outcome results
None listed