Full Macular Hole
Conditions
Brief summary
The notable increase in MPOD following successful surgery suggests its potential role as a valuable adjunctive biomarker associated with a good visual prognosis following this type of macular hole surgical interventions.
Detailed description
Full-thickness macular hole (FTMH) is a debilitating retinal disorder, particularly in its advanced forms, necessitating surgical intervention for vision restoration. This study showes the successful closure of a large FTMH using the inverted flap technique, highlighting the essential role of multimodal imaging, and particularly of macular pigment optical density (MPOD) assessment, in preoperative and postoperative evaluation. Surgery was performed by an expert vitreoretinal surgeon, resulting in significant postoperative improvements in visual acuity and retinal architecture. Multimodal imaging, including MPOD assessment, played a pivotal role in preoperative evaluation and postoperative monitoring.
Interventions
PROCEDURECiro Costagliola
invert flap tecnique
Sponsors
Federico II University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
age older than 60 years * diagnosis of FTHM * absence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration
Exclusion criteria
No diagnosis of pseudophakic cystoid macular oedema * previous treatment for pseudophakic cystoid macular oedema * presence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MPOD After Full-thickness Macular Hole Closure (FTMH) | 6 months | The parameters analyzed by OCT and MPOD six months after surgery are: OCT MPOD visual acuity |
| MPOD and Macula hole: before and after surgery | six months | The parameters analyzed six months after surgery are: MPOD Visual acuity OCT |
Countries
Italy
Outcome results
None listed