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Preventive Effects of Different Volumes of High-Intensity Interval Training on Risk Factors for MS in Overweight Young Women

Preventive Effects of Different Volumes of High-Intensity Interval Training on Risk Factors for Metabolic Syndrome in Overweight Young Women

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06664398
Enrollment
30
Registered
2024-10-29
Start date
2021-04-14
Completion date
2021-11-30
Last updated
2024-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic Syndrome

Keywords

high-intensity interval training, overweight, metabolic syndrome, risk factor, prevention

Brief summary

This study investigates the effects of different volumes of high-intensity interval training on risk factors for metabolic syndrome in overweight young women.

Detailed description

The sedentary and inactive female overweight subjects, aged 18 to 30 years, were randomly divided into three groups: high volume high-intensity interval training group (4HIIT group), low volume high-intensity interval training group (1HIIT group) and control group (CON group). Human morphological measures, blood pressure, insulin resistance, blood analysis, and cardiorespiratory fitness were measured at baseline and after exercise intervention.

Interventions

BEHAVIORALone HIIT

one HIIT high intensity interval training

BEHAVIORALfour HIIT

four HIIT high intensity interval training

Sponsors

Beijing Sport University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Women aged 18-30 years; * BMI≥24kg/m2, indicating overweight and high risk of metabolic syndrome; * Maintaining a stable body weight for the three months prior to the study.

Exclusion criteria

* Regular participation in physical exercise (≥3 times/week, exercise time≥30min/time); * Any respiratory, musculoskeletal, or cardiovascular diseases; * Medical or other contraindications for exercise; * Taking medications that affect metabolism; * Smoking and/or drinking habits.

Design outcomes

Primary

MeasureTime frameDescription
High-density lipoprotein cholesterol (HDL-C)8 weeksChanges in HDL-C before and after intervention.
body fat percentage8 weeksChanges in body fat percentage before and after intervention.
waist circumference (WC)8 weeksChanges in WC before and after intervention.
Systolic blood pressure (SBP)8 weeksChanges in SBP before and after intervention.
Diastolic blood pressure (DBP)8 weeksChanges in DBP before and after intervention.
Fasting plasma glucose (FPG)8 weeksChanges in FPG before and after intervention.
Triglyceride (TG)8 weeksChanges in TG before and after intervention.
Body Mass Index (BMI)8 weeksChanges in BMI before and after intervention.
Weight8 weeksChanges in Weight before and after intervention.

Secondary

MeasureTime frameDescription
Insulin8 weeksChanges in insulin before and after intervention.
Homeostatic model assessment for insulin resistance (HOMA-IR)8 weeks12、Homeostatic model assessment for insulin resistance (HOMA-IR) Changes in HOMA-IR before and after intervention.
Triglyceride-glucose (TyG) index8 weeksChanges in TyG index before and after intervention.
Triglyceride-to-high density lipoprotein cholesterol ratio (TG/HDL-C ratio)8 weeksChanges in TG/HDL-C ratio before and after intervention.
Visceral fat area (VFA)8 weeksChanges in VFA before and after intervention.
Non high-density lipoprotein cholesterol (Non HDL-C)8 weeksChanges in HDL-C before and after intervention.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026