Vascular Function
Conditions
Keywords
Sprint Interval Training, Masked Obesity, Young Women, Ischemic Preconditioning, Vascular Function
Brief summary
Comparison of the effects of combined Sprint Interval Training (SIT) with Remote Ischemic Preconditioning (RIPC) and SIT on vascular function in young women with masked obesity.
Detailed description
This is a randomized clinical trial of single-blind with 3 arms (control group, SIT group and SIT with RIPC group), in which a pre-treatment-posttest design has been used.
Interventions
BEHAVIORALSIT
sprint interval training
BEHAVIORALSIT combined RIPC
sprint interval training combined with remote ischemic preconditioning
Sponsors
Beijing Sport University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Females aged between 18 and 30 years; * BMI within the normal range (18.5～24.9 kg/m²), BF% \> 30%; * Participants with no clinically diagnosed contraindications for exercise, in good health, and not engaged in regular exercise, as determined by the health and physical activity questionnaire (based on the American College of Sports Medicine's guidelines for exercise testing and prescription).
Exclusion criteria
* History of cardiovascular diseases, including coronary heart disease, stroke, or peripheral arterial disease diagnosed through vascular imaging techniques; * Currently participating in other intervention studies, including dietary, nutritional, or psychological education programs; * Those with regular professional training; * Musculoskeletal disorders that make long-term exercise interventions unsuitable.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intima-Media Thickness (IMT) | 8 weeks | Changes in Intima media thickness before and after intervention. |
| Flow-Mediated Dilation (FMD) | 8 weeks | Changes in Flow-mediated dilation before and after Intervention. Brachial artery flow-mediated dilation (FMD) was measured by the UNEXEF high-resolution ultrasound vascular endothelial function analyzer. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood Pressure (BP) | 8 weeks | Changes in blood pressure before and after intervention. Including systolic and diastolic blood pressure. |
| Body Composition Indicator | 8 weeks | Changes in Body composition indicators before and after Intervention. Including body fat percentage (BF%). |
| Maximum Oxygen Uptake (VO2max) | 8 weeks | Changes in maximum oxygen uptake before and after Intervention. |
| Nitric Oxide (NO) | 8 weeks | Changes in concentration of nitric oxide before and after Intervention. |
| Human Morphometric i Indicators | 8 weeks | Changes in Human morphometric indicators before and after Intervention. Including height, weight, waist circumference, hip circumference, and body mass index (BMI). BMI was calculated based on the measured height and weight using the formula: BMI = weight/height² (kg/m²). |
Countries
China
Outcome results
None listed