Cardiovascular System, Health
Conditions
Keywords
Cardiovascular System, Air Pollution Exposure, Acute effect, Weather
Brief summary
The goal of this observational study is to analyze the acute effects of meteorological factors and air pollution on cardiovascular system. The main question it aims to answer is: 1. How do meteorological factors and air pollution affect cardiovascular system? 2. What is the interaction between meteorological factors and air pollution on cardiovascular system? Participants will: 1. Provide their health data obtained in physical examination, including but not limited to blood pressure, blood routine, urine routine and B-ultrasound. 2. agree that the research team will use their personal identification number, gender, age, education level and other information for statistical analysis of the data.
Detailed description
The collected data include: ID number (or unique identification code similar to ID number), physical examination date, work unit, occupation, gender, age, systolic blood pressure, diastolic blood pressure, height, weight, blood routine, urine routine and blood biochemical examination results,Color Doppler (or B-ultrasound) examination results (thyroid color Doppler, abdominal color Doppler, urinary color Doppler, cardiac color Doppler, cervical vascular color Doppler, etc.), electrocardiogram, cardiac CTA, carbon 13 breath test, and written diagnosis results of liver fibrosis.
Interventions
OTHERNOT
This retrospective cohort study involves no new interventions. It analyzes existing health data collected from subjects exposed to varying atmospheric conditions to assess impacts on health outcomes.
Sponsors
The Affiliated Hospital of Hangzhou Normal University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
·Relevant records in the physical examination database shall be ≥3 times ·≥18 years old
Exclusion criteria
* Relevant records in the physical examination database shall be ≥３times * Serious heart and lung diseases * Malignant tumors * Serious mental illness in the past
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Troponin | The troponin data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Troponin data were obtained by blood biochemical detection data recorded in the diagnosis and treatment system, with unit of µg/L. |
| Blood pressure | The blood pressure data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Blood pressure data were obtained from the diagnosis and treatment record system and analyzed by standard sphygmomanometer, with unit of mmHg. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Controlled Attenuation Parameter（CAP） | The Controlled Attenuation Parameter（CAP）data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Controlled Attenuation Parameter（CAP）data were obtained by Diagnosis of hepatic fibrosis data recorded in the diagnosis and treatment system, with unit of dB/m. |
| ST segment of electrocardiogram | The ST segment of electrocardiogram were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | ST segment were obtained by Electrocardiogram (ECG) recorded in the diagnosis and treatment system with unit of mV. |
| Degree of coronary artery stenosis | The degree of coronary artery stenosis data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Degree of coronary artery stenosis data were obtained by Coronary CTA data recorded in the diagnosis and treatment system, with unit of µg/L |
| Left ventricular ejection fraction（LVEF） | The left ventricular ejection fraction（LVEF）data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Left ventricular ejection fraction（LVEF）data were obtained by Cardiac color ultrasound data recorded in the diagnosis and treatment system, with unit of % |
| Height | The height data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Height data were obtained from the diagnosis and treatment record system and recorded by standard measuring tools, with unit of cm |
| Urinary glucose | The urinary glucose data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Urinary glucose data were obtained by Urine routine data recorded in the diagnosis and treatment system, with unit of mmol/L. |
| Weight | The weight data were tested at baseline 3 months before exposure tometeorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | Weight data were obtained from the diagnosis and treatment record system and recorded by standard measuring tools, with unit of kg |
| White cell count | The white cell count data were tested at baseline 3 months before exposure to meteorological factors or air pollution, and followed up for 1 year and 2 years after exposure. | White cell count data were obtained by blood routine blood data recorded in the diagnosis and treatment system, with unit of 10\^9/L |
Countries
China
Contacts
Primary ContactMingwei W Wang, PhD
Outcome results
None listed