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Exercise With Audible Cues on Motor Unit Behavior in Athletes With Anterior Cruciate Ligament Reconstruction

Terminal Knee Extension Exercise Synchronize With Audible Cues on Motor Unit Behavior of Vastus Medialis Muscle in Athletes With Anterior Cruciate Ligament Reconstruction

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06662955
Acronym
ACLR
Enrollment
40
Registered
2024-10-29
Start date
2024-10-20
Completion date
2026-12-30
Last updated
2025-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuromuscular Function, Physical Therapy Techniques, Therapeutic Exercise

Keywords

ACLR

Brief summary

The closed kinetic chain (CKC) of terminal knee extension exercise (TKE) is designed to activate VM activity for knee injury training. This CKC exercise is effective for highest recruiting muscle activity, especially safe for post-operative knee surgery. The study of ACL reconstruction rehabilitation guideline suggests that exercises can be applied within the early phase of rehabilitation to prevent knee laxity and less knee pain compared to open chain exercise. Therefore, it is interesting to investigate the effects of TKE exercise synchronized with metronome pace on change of VM motor unit behavior in post operative ACL reconstruction. This study focuses on the immediate effect of 1-seesion TKE and expects that adding metronome during TKE will enhance neuromuscular control of VM and may change motor unit behavior.

Detailed description

This study investigates the effect of exercise with sensory integration technique on neuromuscular control in athletes with anterior cruciate ligament reconstruction.

Interventions

BEHAVIORALaudible cues

Terminal knee extension exercise with audible cues

BEHAVIORALExercise

Terminal knee extension exercise

Sponsors

Mahidol University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Paticipants are blinded groups allocation.

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

* Male or female participants who receive primary ACL reconstruction within 2 weeks with or without meniscus repair * No or mild resting pain (Numeric rating scale ≤ 3) * Reconstruction procedures using autograft including hamstrings or bone-patella bone grafts * Age range 18-35 years (33). * BMI of 18.5-25 kg/m² (34). * Tegner activity scale ≥ level 4

Exclusion criteria

* Non-weight bearing within 2 weeks after the operation (prescription from surgeon) * Hearing problem, such as being unable to hear the metronome sound or being unable to synchronize exercises with the metronome correctly * Limitations in knee extension range caused by joint stiffness evaluated by using passive knee range of motion * Unable to perform active and passive ≥ 30º knee flexion on the operative side * History of serious injury or operation of lower back and lower extremities such as fracture * Lower back or lower extremities pain within 6 months before the study * On the pain killer medication

Design outcomes

Primary

MeasureTime frameDescription
Average motor unit firing rate (pulse per second, pps)From enrollment to the end of treatment at 2 weeksMotor unit behavior of vastus medialis muscle: Average motor unit firing rate (pulse per second, pps)

Secondary

MeasureTime frameDescription
Peak motor unit action potential (mV)From enrollment to the end of treatment at 2 weeksMotor unit behavior of vastus medialis muscle: Peak motor unit action potential (mV)

Countries

Thailand

Contacts

Primary ContactKomsak Sinsurin, PT, Ph.D., DPT
komsak.sin@mahidol.edu6855547313
Backup ContactSakda Nitkotom, B.Sc.
Sakda.nit@hotmail.com0869853212

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 16, 2026