Chronic Kidney Failure, Functional Capacity, Hemodialysis, Muscle Strength Dynamometer, Physical Activity Level, Sarcopenia
Conditions
Keywords
Chronic Kidney Failure, Hemodialysis, Exercise, Sarcopenia, Muscle strength, Functional capacity, Dynamometer, Physical activity level
Brief summary
People with chronic kidney disease (CKD) undergoing hemodialysis (HD) experience muscular complications, such as sarcopenia, which worsen their functional capacity and increase mortality. Exercise programs during HD are an effective strategy to combat sedentary behavior, and implementing them through innovative technologies could facilitate their adoption in clinics, benefiting more patients. Therefore, the study's objectives are to assess the feasibility and safety of a group exercise program supported by audiovisual media conducted during HD sessions. Additionally, it will analyze factors influencing adherence, identify potential causes for interruptions or failure to perform the prescribed exercise, and evaluate the risk and prevalence of sarcopenia, its association with low muscle strength, poor muscle quality, and physical inactivity.
Detailed description
A 4-week randomized experimental study will be conducted, using an exercise protocol during HD, broadcast simultaneously on television. The frequency of exercise completion, reasons for non-completion, adverse events, as well as sarcopenia, muscle strength, muscle characteristics through ultrasound and electrical bioimpedance, and physical activity levels will be evaluated.
Interventions
OTHERExercise program supported by audiovisual media
The intervention group will perform the group exercise protocol during HD sessions. The videos with the exercises will be broadcast on all televisions simultaneously, so that the volunteers perform the exercises along with the person in the video. * The first level of difficulty includes 5 exercises for the lower limbs and 3 exercises for the upper limbs. One set of 10 repetitions will be performed for each exercise per session. * The second level includes 3 exercises for the lower limbs and 2 exercises for the upper limbs. These consist of proprioceptive neuromuscular facilitation diagonals for both the lower and upper limbs. One set of 10 repetitions will be performed for each exercise, once per week, for 3 weeks. * The third level includes 8 combined lower and upper limb exercises performed simultaneously. One set of 20 repetitions will be performed for each exercise. Exercises will be performed 3 times per week over a 4-week period, for a total of 12 planned exercise sessions.
Sponsors
Cardenal Herrera University
B.Braun Avitum AG
Universidade Federal de Juiz de Fora
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Over 18 years old of both sexes; * Undergoing HD for at least three months in three sessions per week, four hours, totaling 12 hours per week.
Exclusion criteria
* Lower limb amputations; * Neurological, musculoskeletal, or osteoarticular disorders; * Severe and unstable comorbidities; * Undergoing high doses of corticosteroids (\>30 mg/day); * Inability to understand the measurement methods used.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility and Safety Assessment | From start to finish of intervention (4 weeks) | Feasibility will be assessed through adherence rate (number of sessiones performed out of sessions offered). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sarcopenia Risk Assessment | It will be applied before and after the 4 weeks of intervention. | The risk of sarcopenia will be evaluated using the SARC-F (Strength, Assistance with walking, Rising from a chair, Climbing stairs and Falls )questionnaire. Score ranges from 0 a 10, higher scores mean higher risc of sarcopenia. |
| Muscle Strength Assessment | It will be applied before and after the 4 weeks of intervention | Handgrip strength |
| Muscle Characteristics | It will be applied before and after the 4 weeks of intervention | The quantity and quality of muscle mass will be evaluated by the cross-sectional area of the rectus femoris muscle, measured by muscle ultrasound. |
| Physical Activity Level Assessment | It will be applied before and after the 4 weeks of intervention. | The level of physical activity will be evaluated using the HAP questionnaire (Average Activity Score AAS). |
Countries
Spain
Outcome results
None listed