Analgesia, Postoperative
Conditions
Brief summary
To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries
Interventions
dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.
Sponsors
Study design
Eligibility
Inclusion criteria
Age :18 years old and older. Patients undergoing open abdominal surgery.
Exclusion criteria
1. Patient refusal 2. known sensitivity or contraindication to any of study drugs 3. contraindications for local anesthesia 4. Patients with local infection at site of puncture 5. uncooperative patients 6. history of psychological disorders or chronic pain and significant liver or renal disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VAS score | at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative. | pain intensity using VAS score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the time for requirement of first morphine dose | at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative. | the time for requirement of first morphine dose (hours) |