No Condition
Conditions
Keywords
cognitive neuroscience, numerical cognition
Brief summary
Exploring the non-symbolic and symbolic arithmetic competencies in two groups of children (5-, and 7-year-olds). Additionally, we explored the relationship with domain-general factors such as inhibition and attention. Recorded fMRI.
Detailed description
Using T2\*-weighted eip imaging, we measured BOLD response in two cohorts of healthy children while they were doing different cognitive tasks in the scanner. These tasks included solving non-symbolic (i.e. sets of elements) and symbolic (i.e. Arabic digits) addition and subtraction problems, a color control task, an attentional task measuring different facets of spatial attention, and a task measuring inhibition. We also recorded a high-resolution anatomical scan of the brain.
Interventions
OTHERcognitive tasks
no intervention in a medical sense, only observing changes of BOLD signal during different experimental conditions in cognitive tasks (arithmetic, attention, inhibition)
Sponsors
Centre Hospitalier St Anne
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
5 Years to 7 Years
Healthy volunteers
Yes
Inclusion criteria
* school enrollment * French as mother tongue * right-handed * normal medical, neurological and neuroradiological examinations - parents affiliated to a social security scheme
Exclusion criteria
* not within age range * monocygotic twins * \- contraindications to an MRI examination (neurosensory stimulator or implantable defibrillator, cochlear implants, ferromagnetic ocular or cerebral foreign bodies close to nerve structures, metal prostheses, patient agitation: uncooperative or agitated patients, claustrophobic subjects, ventriculoperitoneal neurosurgical shunt valves, dental apparatus, etc.). * sudden onset of cognitive problems that could indicate a stroke; a history of head trauma with loss of consciousness lasting more than 1 hour, or encephalitis; - a chronic neurological, psychiatric, endocrine, hepatic or infectious condition * a history of major illness (diabetes, chronic lung disease, severe cardiac, metabolic, hematological, endocrinological or immunological disorders, cancer); - medication likely to interfere with brain imaging measurements * color blindness or uncorrected visual disorders * inability to take part in the study for geographical or psychiatric reasons * presence of pervasive developmental and/or acquisition disorders identified by parents or legal guardians and/or teachers * cerebral palsy * impaired fine motor skills * parents or legal guardians not affiliated to a social security scheme * unaccompanied by parent(s) or legal guardian(s) during visits. * tattoo not compatible with MRI * children and parents under legal protection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| BOLD response | BOLD response recorded during fMRI session | changes of BOLD response under different experimental conditions (non-symbolic arithmetic; symbolic arithmetic; inhibition; attention) |
Countries
France
Outcome results
None listed