Cataract
Conditions
Keywords
cataract surgery, intraocular lens, extended depth-of-focus
Brief summary
The goal of this clinical trial is to compare the clinical outcomes of two extended depth-of-focus intraocular lens after cataract surgery. The randomized controlled trail will enroll 90 participants. The participants will be randomly assigned to implant Tecnis Synergy ZFR00 or Tecnis Symfony ZXR00 intraocular lens. Follow-up visit will be performed till 3 months postoperatively to compare the visual acuity, subjective manifest refraction, and visual quality between groups.
Interventions
PROCEDUREcataract surgery
The participants will receive femtosecond laser-assisted cataract surgery and implant an extended depth-of-focus intraocular lens (Tecnis Synergy ZFR00).
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* age-related cataract patients aged between 40 to 80 * patients with preoperative astigmatism less than 0.75 D, and kappa value less than 0.7 mm * patients who plan to receive femtosecond laser-assisted cataract surgery
Exclusion criteria
* patients with ocular surface abnormalities such as irregular corneal astigmatism, corneal scarring, keratoconus, and pterygium) * patients with history of ocular trauma or surgery * patients with coexisting ocular disorders such as glaucoma, retinal vascular occlusive disease, retinal detachment, diabetic retinopathy, and any optic nerve-related pathologies * patients with concurrent severe systemic diseases * patients who lack of cooperation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual acuity | 1 day, 1 week, 1 month, 3 months postoperatively | Visual acuity will be assessed using the Standard Logarithmic Visual Acuity Chart. The results will be recorded in decimal and converted to logMAR and Snellen equivalent. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual quality | 3 months postoperatively | OPD-scan measurement. Higher-order aberration, tilt and decentration will be recorded. |
| defocus curve | 3 months postoperatively | Best distance visual acuity varied from - 5.00 to + 2.00 D in steps of 0.50 D under photopic conditions was recorded. |
| contrast sensitivity | 3 months postoperatively | Contrast sensitivity will be converted to logarithmic scale before analysis and referred to as log-contrast sensitivity. |
Countries
China
Contacts
Primary ContactYueyang Zhong, MD.
Outcome results
None listed