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Effect of Cryotherapy and Laser Application on Post-Operative Pain in Single Visit Endodontically Treated Symptomatic Apical Periodontitis Cases

Effect of Cryotherapy and Laser on Post-Operative Pain in Single Visit Endodontically Treated Symptomatic Apical Periodontitis Cases

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06657664
Acronym
LLLT
Enrollment
45
Registered
2024-10-24
Start date
2023-08-01
Completion date
2024-10-10
Last updated
2024-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hot Tooth, Irriversible Pulpitis With Apical Peridontitis

Keywords

cryotherapy Low Level Laser Therapy LLLT single visit endodontic treatment irriversible pulpitis Apical peridontitis

Brief summary

This study compare the effect of applying ice after single visit endodontic treatment with lasers to reduce post operative pain .

Detailed description

one of the most popular complications after single visit endodontic treatment is pain either spontaneous or on biting so in this study we choose one of the most difficult and challenging cases Hot tooth to compare lasers and cryotherapy different applications to reduce post operative pain after single visit endodontic treatment

Interventions

the root canals are given a final irrigation with 20 mL cold (2.5oC) saline solution for 5 minutes before obturation

PROCEDUREintaoral cryotherapy

ice sticks (wrapped in sterile gauze if needed) using plastic pipette droppers filled with freezed sterile water are placed intraorally in the mouth on the apices of the treated tooth on both buccal and palatal sides for 30 minutes

PROCEDUREBoth intracanal and intraoral cryotherapy

Canal is irrigated with iced saline for 5 minutes before obturation . Root canal is obturated and coronal restoration is done. Then, application of intraoral cryotherapy is performed by ice sticks for 30 minutes.

DEVICELow Level Laser Therapy

laser irradiation on the soft tissues covering the apices of the tooth on both buccal and palatal surfaces respectively

PROCEDUREControl (Standard treatment)

, all occlusal contacts were reduced by 1 mm

Sponsors

Tanta University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Masking description

all participants have an equal chance to be enrolled in any of the study groups. This pattern was the most suitable way to ensure the balance of the anonymous prognostic factors in the participants between the three groups thus, eliminating the selection or allocation bias

Intervention model description

This is a randomized clinical study.

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* • Vital teeth display symptomatic apical periodontitis (Symptomatic apical periodontitis was determined based on the clinical symptoms of severe preoperative pain (visual analogue scale \[VAS\] \> 60) and severe percussion pain (VAS \> 60). * Teeth, with a periapical index score (PAI) of 2 or 3 indicating small changes in bone structure and slight mineral loss respectively. * Mobility less than 1 mm in either direction. * Absence of periodontal pocket around the tooth. * Symptomatic pulpitis with spontaneous pain or lingered by cold or heat. * Teeth without pus or inflammatory exudates draining through the canal. * Teeth without anatomic variations

Exclusion criteria

* • Patient with any systemic disease. * Immunocompromised patients. * Pregnant or lactating patients. * Apparently narrow roots in which apical preparation with the #40 file would be overzealous. * Retreatment cases. * Necrotic painful teeth with absence of sinus tract for drainage. * Patients on analgesics or sedative medication up to 6 hours before treatment

Design outcomes

Primary

MeasureTime frameDescription
post operative painpreoperative, after 24 hours, on the third , fifth, one week & two weeks after treatmentpost operative pain and pain on percussion is tested using visual analogue scale

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026