IMMEDIATE IMPLANT With Different Types of Membranes

Autogenous Dentine Derived Barrier Membrane Versus Extended Platelet Rich Fibrin Membrane in Immediate Implant Placement

Status

Enrolling by invitation

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06657651

Enrollment

Registered

2024-10-24

Start date

2024-06-30

Completion date

2025-06-01

Last updated

2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Extraction

Brief summary

forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area. Patients' Grouping: The patients will be randomly divided into two equal uniform groups each consists of 20 patients: Group A: 20 patients with non-restorable mandibular molar tooth will be treated with an immediately placed dental implant in conjunction with a dentin-derived membrane from the extracted tooth. Group B: 20 patients with non-restorable mandibular molar tooth will be treated with an immediately placed dental implant in conjunction with extended platelet rich fibrin membrane.

Interventions

PROCEDUREimmediate implant placement with dentin-derived membrane

immediate implant placement with dentin-derived membrane and allograft in mandibular molar area

PROCEDUREimmediate implant with extended platelet rich fibrin membrane

immediate implant with extended platelet rich fibrin membrane and allograft in mandibular molar area

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Age above 18 years * Non-restorable mandibular molar tooth that needs dental extraction & guided bone regeneration for immediate implant placement. * Acceptable inter-arch space for the future prosthesis. * Patient medically free from systemic diseases that absolutely contraindicate implant surgery. * Cooperative patient with high motivation and acceptable oral hygiene. * Free from history of bruxism / parafunctional habits.

Exclusion criteria

* Local and / or systemic conditions that interfere with the procedure. * Smokers. * Pregnancy. * Uncooperative patients. * Patient had undergone in the past 12 months radiation therapy to the head and neck area.

Design outcomes

Primary

Measure	Time frame	Description
Implant stability	1 year	Osstell will be used to record implant stability at the placement time, 3, 6 and 12 months after surgery.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026