Enabling Microbiomics- Driven Personalized Nutrition

Enabling Microbiomics- Driven Personalized Nutrition (EMPOWER)

Status

Enrolling by invitation

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06657001

Acronym

EMPOWER

Enrollment

4001

Registered

2024-10-24

Start date

2025-03-28

Completion date

2028-04-01

Last updated

2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Celiac Disease, Constipation, Crohn's Disease, Diarrhea, Functional Dyspepsia, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Microbiome, Microscopic Colitis, UC - Ulcerative Colitis

Keywords

GI Disorders, Microbiomics, Diet, Microbiome, Nutrition, GI Function

Brief summary

The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions. The main question investigators aim to answer is: Are host genetics, diet, and microbiome all important determinants of GI disorders, and how their relative contribution varies among individuals and populations.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age greater than or equal to 18 years * Gastrointestinal patients with or without genomic sequencing results available for the following cohorts: * Inflammatory Bowel Disease (IBD) * Irritable Bowel Syndrome (IBS) * Crohn's Disease * Celiac Disease * Diarrhea * Constipation * Healthy age and sex matched controls with or without genomic sequencing results available o Control is defined as patients without gastrointestinal disease or no symptoms at time of sampling * Able to provide written, informed consent * Participant has a smartphone device with access to internet connection

Exclusion criteria

* Patients with cognitive impairment * Active use of antibiotics at the time of stool collection

Design outcomes

Primary

Measure	Time frame	Description
To Correlate Differences in Diet and Microbiome with Different GI Symptoms and Disease States	From enrollment through study completion, an average of 1 year.	Investigators will prospectively follow the clinical course of the patients throughout the duration of the study. Patient health outcomes will be documented from their medical record while the study is actively enrolling or undergoing data analysis.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORPurna Kashyap, MBBS

Mayo Clinic

Outcome results