Colon Cancer
Conditions
Keywords
Colon Cancer, Prognosis, Tumor-associated inflammatory adhesion
Brief summary
The purpose of this study is to explore the impact of tumor-associated inflammatory adhesion on the prognosis of colon cancer patients.
Detailed description
In some colon cancer patients, although adhesions between the tumor tissue and surrounding organs are found during surgery, postoperative pathology confirms that the tumor has not directly invaded the adhered organs; instead, the adhesions are caused by tumor-associated inflammation. This condition is defined as tumor-associated inflammatory adhesion. Currently, the impact of tumor-associated inflammatory adhesion on patient prognosis is still unclear. This study aims to explore the impact of tumor-associated inflammatory adhesion on the prognosis of colon cancer patients through the Surveillance, Epidemiology, and End Results (SEER) and Chinese multi-center databases.
Interventions
OTHERThis was a retrospective study and no patient intervention was performed.
This was a retrospective study and no patient intervention was performed.
Sponsors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
1. The patient was pathologically diagnosed as colon adenocarcinoma by endoscopic biopsy before operation. 2. All patients were considered to have tumors invading adjacent organs during surgery 3. All patients underwent radical surgery.
Exclusion criteria
1\. Patients with distant metastasis, recurrent colon cancer and pT4b CRC were excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival time (OS) | up to 10 years | OS, defined as the time from the first diagnosis to death from any cause or the last follow-up for surviving patients |
| Cancer-specific survival time (CSS) | up to 10 years | CSS refers to the duration from diagnosis of a tumor until the patient succumbs to the tumor, excluding deaths from other causes. |
| Recurrence free survival time (RFS) | up to 10 years | RFS is the time from the time a patient achieved R0 resection after surgery to the time of recurrence or the end of follow-up. |
Countries
China
Outcome results
None listed