The Conus Brugada Syndrome Study

The CONUS-BRS STUDY: An Observational, Analytical, Cross Sectional Study Investigating the Effects of Conus Branch and Right Ventricular (RV) Branch Occlusion on Surface ECG and Intra-cardiac Electrograms in Patients Undergoing Percutaneous Coronary Intervention (PCI)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06653504

Acronym

Conus-BRS

Enrollment

Registered

2024-10-22

Start date

2018-11-05

Completion date

2020-11-06

Last updated

2024-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brugada Syndrome

Brief summary

An observational, analytical, cross sectional study investigating the effects of Conus branch and Right Ventricular (RV) Branch occlusion on surface ECG and intra-cardiac electrograms in patients undergoing percutaneous coronary intervention (PCI).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Aged 18-85 * Patients able and willing to give their written informed consent. * Planned PCI of a CTO of a right coronary artery * Planned use of an anchor balloon in the Conus branch or RV branch

Exclusion criteria

* Patients considered unsuitable to participate by the research team (e.g., due to medical reasons, laboratory abnormalities, or subject's unwillingness to comply with all study related procedures). * Patients with a pre-existing, confirmed or possible diagnosis of Brugada Syndrome * Marked ST elevation or J point elevation on baseline (prior to procedure) ECG in the precordial leads (V1-V3) * Pregnancy. This will be tested by urine HcG measurement

Design outcomes

Primary

Measure	Time frame	Description
ECG and/or electrogram changes	During Procedure	Incidence of ECG changes resembling a Brugada type 1 pattern of coved ST elevation (one of the three Brugada types) specifically significant J point elevation in the precordial leads (V1-V3) and/or electrogram changes on the epicardial and/or endocardial intracardiac traces which will then be compared for differences and evidence of a transmural voltage gradient existing between them.

Countries

United Kingdom

Outcome results