Osteoarthritis of Knee
Conditions
Brief summary
Total Knee Replacement surgery is common procedure that is usually done for patients suffering from persistent pain with limitation of movement. Unfortunately, they do suffer after the operation as it is associated still with significant pain that affect the rehabilitation plan, hospital length of stay, life style and patient satisfaction. New approaches are rising every day to add to the multimodal management plan. Genicular nerves cooled radiofrequency ablation is a new approach that can be simply done U.S. guided with little side effects, if any, and great results.
Detailed description
the study measures the efficacy of genicular nerves cooled radiofrequency ablation in enhancing quality of rehabilitation in patients undergoing total knee replacement
Interventions
PROCEDUREunilateral Radiofrequency
unilateral genicular nerve cooled radio frequency ablation pre-operative
PROCEDUREbilateral Radiofrequency
bilateral genicular nerve cooled radio frequency ablation pre-operative
PROCEDUREEpidural
Patients will receive epidural anesthesia intra operative and epidural analgesia post-operative
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• Undergoing a scheduled unilateral total knee replacement surgery \-
Exclusion criteria
* • Allergy to any of the drugs used in the study * Alcohol or drug abuse * Psychiatric disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| o Epidural rescue doses | 1st 48 hours | rescue doses reflects degree of pain control |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| WOMAC score | baseline preoperative, and the at 2, 6 and 12 weeks postoperative | assessment of the functional state of the patient and degree of pain and limitation of movement |
| Knee range of motion | Assessed weekly for 3 weeks postoperatively (Weeks 1, 2, and 3) | Time to achieve full knee range of motion will be assessed by measuring active knee flexion and extension in degrees (°) using a universal goniometer during weekly postoperative assessments. The outcome will be reported as the number of days or weeks required to achieve full range of motion, as defined in the study protocol. |
| Postoperative inflammatory signs assessed by clinical examination | Assessed weekly for 3 weeks postoperatively (Weeks 1, 2, and 3). | Postoperative inflammatory signs, including redness (erythema), local warmth, and swelling around the operated knee, will be assessed by clinical examination. Each sign will be recorded as present or absent. The outcome will be reported as the number of participants with each inflammatory sign at each assessment. |
Countries
Egypt
Outcome results
None listed