Neonatal Jaundice
Conditions
Brief summary
Neonatal jaundice frequently occur during initial week of life. Neonatal jaundice is one of the leading causes of hospital admission and readmission. Some studies have suggested that the healthy newborns with hyperbilirubinemia outside the physiological range have notably reduced serum vitamin D levels. This deficiency is inversely associated with neonatal hyperbilirubinemia, suggesting that low vitamin D levels could be a potential risk factor for jaundice among neonates.
Interventions
DRUGVitamin D
Vitamin D supplementation as vitamin D, 2 drops i.e., 800 IU daily for 5 days.
Sponsors
Muhammad Aamir Latif
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Randomized controlled trial
Eligibility
Sex/Gender
ALL
Age
3 Days to 28 Days
Healthy volunteers
No
Inclusion criteria
* Both genders * Admitted between 3-28 days of age. * Indirect hyperbilirubinemia with TSB levels between 14-20 mg/dL * Born via either cesarean or vaginal delivery * Birth weight greater than 2500 grams
Exclusion criteria
* Prior phototherapy treatment * Preterm birth (gestational age below 37 weeks). * SpO2 \< 95% at the time of admission * Severe respiratory distress or failure * Neonatal sepsis * Congenital anomalies * Parents/guardians unwilling to let their neonates be part of this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total Serum bilirubin levels | 5 days | Total Serum bilirubin levels evaluated |
Countries
Pakistan
Outcome results
None listed