Assessment of Rapid Osseointegration of Dental Implants with Different Coatings

Assessment of Osseointegration of Dental Implants with Three Different Coatings for Early Loading Purpose and Marginal Bone Loss in the Posterior Maxilla. a Randomized Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06650280

Enrollment

Registered

2024-10-21

Start date

2023-02-01

Completion date

2024-06-01

Last updated

2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implants, Hyaluronic Acid

Keywords

dental implants, rapid osseointegration, early loading

Brief summary

The study will assess early osseointegration of dental implant with three different coating materials through secondary implant stability

Detailed description

Dental implants with sandblasted acid itched coating, nano-hydroxyapatite coating, and hyalouronic acid coating will be placed in the posterior maxilla to restore a missing tooth. Implant stability by the use of Ostell will be measured immediately post-operative, 4, 6, and 12 weeks post-operative. marginal bone loss around the implants will be compared immediately after final restoration delivery and after one year

Interventions

OTHERHyaluronic Acid (HA)

hyaluronic acid coated implants will be placed in posterior maxilla to evaluate rapid osseointegration

OTHERnano-hydroxyapatite

nano-hydroxyapatite coated implants will be placed in posterior maxilla to assess rapid osseointegration

OTHERsandblasted acid etched

SLA coated implants will be placed in posterior maxilla and implant stability will be evaluated

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 49 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients with missing at least one maxillary posterior tooth 2. Patients free from any systemic disease 3. Patients who approve to be included in the trial and sign the informed consent 4. Patients with no intra-bony defect. 5. Adults aged 18 years old and above

Exclusion criteria

1. Patients who are allergic to titanium 2. Heavy smoker patient 3. Patients receiving chemotherapy or radiotherapy 4. Patients who refused to be included in the trial

Design outcomes

Primary

Measure	Time frame	Description
rapid osseintegration	immediately post-operative, 4, 6, and 12 weeks post-operative	rapid osteointegration of dental implants will be evaluated by the use of Ostell device which measures primary and secondary stability expressed as ISQ measures ranging from zero till 90

Secondary

Measure	Time frame	Description
marginal bone loss	immediately after final restoration delivery and one year post-operative	the bone height from implant's platform till implant's tip will be measured and compared between immediately after final restoration delivery and after one year

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026