Hemorrhoids
Conditions
Brief summary
Endoscopic superior rectal mucosal ligation and hemorrhoids ligation are two types of endoscopic ligation, The aim of this study is to compare the clinical efficacy and safety of these two approaches.If you accept this study,you need to provide case information before the operation, complete the endoscopic treatment according to the routine colonoscopy procedure, and follow-up survey after the operation.
Interventions
PROCEDUREEndoscopic superior rectal mucosal ligation
The patient takes the left side decubitus position, the endoscope is connected with 6 serial ligators, the cup of the sleeve is pointed at the upper edge of the straight anal line and the rectal mucosa is continuously aspirated under negative pressure. The mucosa enters the sleeve and sees a full-screen red sign. The sensing loop is successfully triggered, indicating that the loop is complete.
PROCEDUREEndoscopic hemorrhoid ligation
The patient takes the left side decubitus position,the endoscope is connected with 6 serial ligators,the cup the sleeve is aligned with the base of the hemorrhoid (above the dentate line) for continuous negative pressure suction.The hemorrhoid enters the sleeve and sees a full-screen red sign. Turn the handle of the sleeve clockwise and feel that the loop is successfully triggered, the ligature is completed.
Sponsors
The Affiliated Hospital of Qingdao University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
1. According to the Goligher classification in the Chinese guidelines for the diagnosis and treatment of hemorrhoids (2020) , patients who are diagnosed with grade II-III internal hemorrhoids . 2. Patients who voluntarily participate and sign the informed consent form.
Exclusion criteria
1. patients who had severe heart, liver, and kidney disease. 2. patients who had severe immune deficiency. 3. patient's general condition is too poor to tolerate endoscopic therapy. 4. patients had a history of pelvic chemoradiotherapy. 5. patients had severe infection or inflammatory lesion in the rectum or anal canal,or the rectum or anal canal had undergone surgery. 6. patient is a pregnant woman. 7. patients who disagree with endoscopic treatment and are concerned about the possible risks refused to sign the informed consent form. 8. the follow-up time is insufficient and the clinical data were incomplete.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| complication | 7 days after operation | Postoperative complications, such as dysuria, thrombotic external hemorrhoids, perianal abscess,and so on. |
| clinical efficacy | 1 month after operation | Complete disappearance of postoperative symptoms is regarded as a cure, postoperative symptoms relief is regarded as partial cure, and symptoms as same as before are considered ineffective. |
Contacts
Primary ContactNa Zu
Outcome results
None listed